User profiles for Qiuyin Cai

Qiuyin Cai

Vanderbilt University Medical Center
Verified email at vanderbilt.edu
Cited by 39145

Association analysis identifies 65 new breast cancer risk loci

…, T Brüning, B Burwinkel, K Butterbach, Q Cai, H Cai… - Nature, 2017 - nature.com
Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as
BRCA1, and many common, mostly non-coding variants. However, much of the genetic …

A saturated map of common genetic variants associated with human height

…, JA Brody, KS Burgdorf, BE Cade, H Cai, Q Cai… - Nature, 2022 - nature.com
Common single-nucleotide polymorphisms (SNPs) are predicted to collectively explain 40–50%
of phenotypic variation in human height, but identifying the specific variants and …

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

…, E Boerwinkle, LL Bonnycastle, N Burtt, Q Cai… - Nature …, 2014 - nature.com
To further understanding of the genetic basis of type 2 diabetes (T2D) susceptibility, we
aggregated published meta-analyses of genome-wide association studies (GWAS), including …

Antioxidant and antipromotional effects of the soybean isoflavone genistein

H Wei, R Bowen, Q Cai, S Barnes… - Proceedings of the …, 1995 - journals.sagepub.com
Antioxidant and Antipromotional Effects of the Soybean Isoflavone Genistein - Huachen Wei,
Ronald Bowen, Qiuyin Cai, Stephen Barnes, Yan Wang, 1995 … Qiuyin Cai

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

…, RCW Ma, K Yamamoto, LS Adair, T Aung, Q Cai… - Nature …, 2012 - nature.com
We conducted a three-stage genetic study to identify susceptibility loci for type 2 diabetes (T2D)
in east Asian populations. We followed our stage 1 meta-analysis of eight T2D genome-…

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

…, EM Kwon, DM Karyadi, WJ Blot, W Zheng, Q Cai… - Nature …, 2013 - nature.com
Prostate cancer is the most frequently diagnosed cancer in males in developed countries.
To identify common prostate cancer susceptibility alleles, we genotyped 211,155 SNPs on a …

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

…, MP Zamora, JIA Perez, XO Shu, W Lu, YT Gao, H Cai… - Nature …, 2015 - nature.com
Genome-wide association studies (GWAS) and large-scale replication studies have identified
common variants in 79 loci associated with breast cancer, explaining ∼14% of the familial …

Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25. 1

…, S Levy, SL Deming, JL Haines, K Gu, AM Fair, Q Cai… - Nature …, 2009 - nature.com
We carried out a genome-wide association study among Chinese women to identify risk
variants for breast cancer. After analyzing 607,728 SNPs in 1,505 cases and 1,522 controls, we …

[PDF][PDF] Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps

…, WM Grady, W Zheng, MK Washington, Q Cai… - Cell, 2021 - cell.com
Colorectal cancers (CRCs) arise from precursor polyps whose cellular origins, molecular
heterogeneity, and immunogenic potential may reveal diagnostic and therapeutic insights …

Meta-analysis identifies common variants associated with body mass index in east Asians

…, BE Henderson, H Song, A Tan, J He, DPK Ng, Q Cai… - Nature …, 2012 - nature.com
Multiple genetic loci associated with obesity or body mass index (BMI) have been identified
through genome-wide association studies conducted predominantly in populations of …