To investigate the global expression profile of miRNAs in primary breast cancer (BC) and
normal adjacent tumor tissues (NATs) and its potential relevance to clinicopathological …

The Bmi-1 oncoprotein regulates proliferation and oncogenesis in human cells. Its
overexpression leads to senescence bypass in human fibroblasts and immortalization of human …

Introduction MicroRNAs (miRNAs) are a class of small non-coding RNAs (20 to 24 nucleotides)
that post-transcriptionally modulate gene expression. A key oncomir in carcinogenesis is …

Lung cancer ranks as the most common and lethal malignancy in America and worldwide.
APOBEC3B is a newly identified DNA cytosine deaminase, which is supposed to function as a …

The microRNA miR-125b is dysregulated in various human cancers but its underlying
mechanisms of action are poorly understood. Here, we report that miR-125b is downregulated in …

BACKGROUND Serologic measurement of antibodies to Epstein–Barr virus (EBV) immunoglobulin
A/viral capsid antigen (IgA/VCA) and early antigen (IgA/EA) has been used widely to …

Objective: The aim of this study was to determine the biological significance of glucose
transporter (Glut)-1 and Glut-3 expression in head and neck carcinoma (HNC). Methods: We …

Background and aims A previous study of ours indicated that enhancer of zeste homologue
2 (EZH2) plays an important role in hepatocellular carcinoma (HCC) tumorigenesis. The aim …

Amplification of 3q26 is one of the most frequent chromosomal alterations in many solid
tumors, including ovarian, lung, esophageal, prostate, breast, and nasopharyngeal cancers. A …

Esophageal squamous dysplasia is believed to be the precursor lesion of esophageal
squamous cell carcinoma (ESCC); however, the genetic evolution from dysplasia to ESCC …