[HTML][HTML] The molecular biology of pancreatic adenocarcinoma: Translational challenges and clinical perspectives

…, DL Fu, C Bruns, Y Zhao, LX Qin, QZ Dong - Signal transduction and …, 2021 - nature.com
Pancreatic cancer is an increasingly common cause of cancer mortality with a tight correspondence
between disease mortality and incidence. Furthermore, it is usually diagnosed at an …

[PDF][PDF] MicroRNA‐26a suppresses tumor growth and metastasis of human hepatocellular carcinoma by targeting interleukin‐6‐Stat3 pathway

…, JW Wei, HJ Zhou, N Ren, QH Ye, QZ Dong… - …, 2013 - Wiley Online Library
Down‐regulation of microRNA‐26a (miR‐26a) is associated with poor prognosis of hepatocellular
carcinoma (HCC), but its functional mechanism in HCC remains unclear. In this study, …

Disruption of tumour-associated macrophage trafficking by the osteopontin-induced colony-stimulating factor-1 signalling sensitises hepatocellular carcinoma to anti …

…, Y Zheng, Y Zhao, L Lu, HL Jia, MC Hung, QZ Dong… - Gut, 2019 - gut.bmj.com
Objective In the tumour microenvironment, critical drivers of immune escape include the
oncogenic activity of the tumour cell-intrinsic osteopontin (OPN), the expression of programmed …

[HTML][HTML] Isolation and characterization of exosomes for cancer research

…, WW Zhu, Y Geng, L Lu, H Jia, LX Qin, QZ Dong - Journal of hematology & …, 2020 - Springer
Exosomes are a subset of extracellular vesicles that carry specific combinations of proteins,
nucleic acids, metabolites, and lipids. Mounting evidence suggests that exosomes …

[PDF][PDF] GOLM1 modulates EGFR/RTK cell-surface recycling to drive hepatocellular carcinoma metastasis

…, HL Jia, L Lu, XF Zhang, BF Lian, L Xie, QZ Dong… - Cancer cell, 2016 - cell.com
The mechanism of cancer metastasis remains poorly understood. Using gene profiling of
hepatocellular carcinoma (HCC) tissues, we have identified GOLM1 as a leading gene relating …

[PDF][PDF] Lentiviral‐mediated miRNA against osteopontin suppresses tumor growth and metastasis of human hepatocellular carcinoma

BS Sun, QZ Dong, QH Ye, HJ Sun, HL Jia, XQ Zhu… - …, 2008 - Wiley Online Library
Lentiviralâ•’mediated miRNA against osteopontin suppresses tumor growth and metastasis
of human hepatocellular carcinoma< Page 1 Lentiviral-Mediated miRNA Against …

[PDF][PDF] MicroRNA‐26a suppresses angiogenesis in human hepatocellular carcinoma by targeting hepatocyte growth factor‐cMet pathway

X Yang, XF Zhang, X Lu, HL Jia, L Liang, QZ Dong… - …, 2014 - Wiley Online Library
MicroRNA (miR)‐26a can suppress tumor growth and metastasis of hepatocellular carcinoma
(HCC). Since angiogenesis is important for tumor growth and metastasis, we investigated …

[HTML][HTML] Characteristics of the cancer stem cell niche and therapeutic strategies

…, S Gul, R Vago, CJ Bruns, Y Zhao, QZ Dong… - Stem Cell Research & …, 2022 - Springer
Distinct regions harboring cancer stem cells (CSCs) have been identified within the
microenvironment of various tumors, and as in the case of their healthy counterparts, these …

Evaluation of midkine as a diagnostic serum biomarker in hepatocellular carcinoma

…, M Forgues, H Huang, XJ Xing, N Ren, QZ Dong… - Clinical Cancer …, 2013 - AACR
Purpose: To evaluate the value of serum midkine (MDK) as a diagnostic biomarker in
hepatocellular carcinoma, particularly for those with negative alpha-fetoprotein (AFP) and at an …

Human mesenchymal stem cells inhibit metastasis of a hepatocellular carcinoma model using the MHCC97‐H cell line

…, N Ren, HL Jia, J Shi, JC Wu, C Dai, QZ Dong… - Cancer …, 2010 - Wiley Online Library
The effects of mesenchymal stem cells (MSC) on the growth and metastasis of human
malignancies including hepatocellular carcinoma (HCC) are controversial, and the underlying …