Faecalibacterium prausnitzii‐derived microbial anti‐inflammatory molecule regulates intestinal integrity in diabetes mellitus mice via modulating tight junction protein …
…, K Tian, J Li, X Chen, T Yu, Q Chen - Journal of …, 2020 - Wiley Online Library
Background Impaired intestinal barrier structure and function have been validated as an
important pathogenic process in type 2 diabetes mellitus (T2DM). Gut dysbiosis is thought to be …
important pathogenic process in type 2 diabetes mellitus (T2DM). Gut dysbiosis is thought to be …
Rebamipide helps defend against nonsteroidal anti-inflammatory drugs induced gastroenteropathy: a systematic review and meta-analysis
…, H Mao, W Zhu, Q Chen, Y Zhang, Y Chen - Digestive diseases and …, 2013 - Springer
Background Gastrointestinal toxicity of nonsteroidal anti-inflammatory drugs (NSAIDs) has
been perplexing most clinicians and users of NSAIDs. Rebamipide is increasingly advocated …
been perplexing most clinicians and users of NSAIDs. Rebamipide is increasingly advocated …
[HTML][HTML] m6A methyltransferase METTL3 maintains colon cancer tumorigenicity by suppressing SOCS2 to promote cell proliferation
J Xu, Q Chen, K Tian, R Liang, T Chen… - Oncology …, 2020 - spandidos-publications.com
N6‑methyladenosine (m6A) RNA modification maintained by N6‑methyltransferases and
demethylases is involved in multiple biological functions. Methyltransferase like 3 (METTL3) is …
demethylases is involved in multiple biological functions. Methyltransferase like 3 (METTL3) is …
Gastroesophageal Reflux Disease Questionnaire (GerdQ) in real‐world practice: a national multicenter survey on 8065 patients
…, Y Zou, Y Li, M Sun, Q Chen, M Chen… - Journal of …, 2013 - Wiley Online Library
Background and Aim Recently, Gastroesophageal Reflux Disease Questionnaire ( GerdQ )
has been developed for diagnosis of GERD . However, no study investigated its value in real‐…
has been developed for diagnosis of GERD . However, no study investigated its value in real‐…
The investigation of polymer-siRNA nanoparticle for gene therapy of gastric cancer in vitro
…, Y Chen, K Huang, X Shuai, Q Chen… - International journal …, 2010 - Taylor & Francis
Small interfering RNA (siRNA) molecules have significant therapeutic promise for the genetic
treatment of cancer. To overcome instability and low transfection efficiency, polyethylene …
treatment of cancer. To overcome instability and low transfection efficiency, polyethylene …
LncRNA DICER1‐AS1 promotes colorectal cancer progression by activating the MAPK/ERK signaling pathway through sponging miR‐650
W Li, C Ke, C Yang, J Li, Q Chen, Z Xia… - Cancer Medicine, 2023 - Wiley Online Library
Background Colorectal cancer (CRC) is a disease with high morbidity and mortality rates
globally. Long noncoding RNAs (lncRNAs) play a fundamental role in tumor progression, and …
globally. Long noncoding RNAs (lncRNAs) play a fundamental role in tumor progression, and …
High glucose‐induced intestinal epithelial barrier damage is aggravated by syndecan‐1 destruction and heparanase overexpression
…, Y Chen, R Li, H Mao, Q Chen - Journal of cellular and …, 2015 - Wiley Online Library
Syndecan‐1 (Sdc1) and its endo‐beta‐d‐glucuronidase heparanase ( HPSE ) are implicated
in maintenance of intestinal epithelial barrier ( IEB ), but their alterations and roles in high‐…
in maintenance of intestinal epithelial barrier ( IEB ), but their alterations and roles in high‐…
AKT and JNK signaling pathways increase the metastatic potential of colorectal cancer cells by altering transgelin expression
H Zhou, Y Zhang, Q Chen, Y Lin - Digestive diseases and sciences, 2016 - Springer
Background Transgelin (SM22) plays a crucial role in colorectal cancer (CRC) progression;
nevertheless, its upstream regulatory mechanisms are poorly defined. AKT and JNK …
nevertheless, its upstream regulatory mechanisms are poorly defined. AKT and JNK …
[HTML][HTML] Effects of hemicellulose on intestinal mucosal barrier integrity, gut microbiota, and metabolomics in a mouse model of type 2 diabetes mellitus
H Liu, J Xu, C Yeung, Q Chen, J Li - Frontiers in Microbiology, 2023 - frontiersin.org
Background and objective Impaired gut barrier contributes to the progression of type 2
diabetes mellitus (T2DM), and the gut microbiota and metabolome play an important role in it. …
diabetes mellitus (T2DM), and the gut microbiota and metabolome play an important role in it. …
Specific reversal of MDR1/P-gp-dependent multidrug resistance by RNA interference in colon cancer cells
…, Z Zhu, L Zhang, C Royal, Z Liu, Q Chen… - Oncology …, 2008 - spandidos-publications.com
No control cell line was available for previous RNA interference studies on reversal of multidrug
resistance (MDR) in colon cancer cells. Here, human COLO 320DM, with HT-29 as the …
resistance (MDR) in colon cancer cells. Here, human COLO 320DM, with HT-29 as the …
