Objective It is believed that the variable effectiveness of somatostatin analogs in post-surgical
management of somatotropinomas and non-functioning pituitary adenomas (NFPA) may …

The ATP-binding cassette transporters (ABC transporters) have been intensely studied over
the past 50 years for their involvement in the multidrug resistance (MDR) phenotype, …

Acquired resistance during cancer treatment is unfortunately a frequent event. There are
several reasons for this, including the ability of the ATP-binding cassette transporters (ABC …

Glioblastoma is an extremely aggressive and deadly brain tumor known for its striking cellular
heterogeneity and capability to communicate with microenvironment components, such as …

Abstract Knowledge of viral load is essential to formulate strategies for antiviral treatment,
vaccination, and epidemiological control of COVID-19. Moreover, identification of patients with …

Background Glioblastoma is a fatal brain tumour with a poor patient survival outcome. Hypoxia
has been shown to reprogram cells towards a stem cell phenotype associated with self-…

Pituitary apoplexy is a rare and life-threatening clinical condition caused by hemorrhage and/or
infarction of the pituitary gland or adenoma. Although pituitary apoplexy is usually …

… Carlos Pilotto Heming: wrote the present review; Veronica Aran: conceived, designed and
wrote the present review; Vivaldo Moura Neto and Paulo Niemeyer Filho critically reviewed …

Objective Venous thromboembolism (VTE) is particularly prevalent in neurosurgical patients.
A major dilemma arises when a patient needs to be treated with therapeutic …

Background: Convalescent plasma is a potential therapeutic option for critically ill patients
with coronavirus disease 19 (COVID-19), yet its efficacy remains to be determined. The aim …