Mesenchymal stromal cells (MSCs) are multipotent cells, immunomodulatory stem cells that
are currently used for regenerative medicine and treatment of a number of inflammatory …

Master developmental pathways, such as Notch, Wnt, and Hedgehog, are signaling systems
that control proliferation, cell death, motility, migration, and stemness. These systems are …

Mesenchymal stromal cells (MSCs) are adult, multipotent cells of mesodermal origin
representing the progenitors of all stromal tissues. MSCs possess significant and broad …

Both preclinical and clinical investigations suggest that Notch signalling is critical for the
development of many cancers and for their response to chemotherapy. We previously showed …

Mesenchymal stromal cells (MSCs) are adult multipotent stem cells residing as pericytes in
various tissues and organs where they can differentiate into specialized cells to replace …

Notch and Wnt signaling are highly conserved intercellular communication pathways involved
in developmental processes, such as hematopoiesis. Even though data from literature …

Mesenchymal stem/stromal cells (MSCs) are multipotent cells residing in the stromal tissues
of the body and capable of promoting tissue repair and attenuating inflammatory processes …

Master developmental pathways, such as Notch, Wnt, and Hedgehog, are signaling systems
that control proliferation, cell death, motility, migration, and stemness. These systems are …

In this study, we compared the overall gene and pathway expression profiles of HS-5 and
HS-27A stromal cell lines with those of primary bone marrow MSCs to verify if they can be …

Graft-vs-host-disease (GvHD) is currently the main complication of allogeneic hematopoietic
stem cell transplantation. Mortality and morbidity rates are particularly high, especially in …