CRISPR–Cas9 in genome editing: Its function and medical applications
…, RA Motlagh, N Farahani… - Journal of cellular …, 2019 - Wiley Online Library
The targeted genome modification using RNA‐guided nucleases is associated with several
advantages such as a rapid, easy, and efficient method that not only provides the …
advantages such as a rapid, easy, and efficient method that not only provides the …
[HTML][HTML] The role of efferocytosis in autoimmune diseases
F Abdolmaleki, N Farahani, SM Gheibi Hayat… - Frontiers in …, 2018 - frontiersin.org
Apoptosis happens continuously for millions of cells along with the active removal of
apoptotic debris in order to maintain tissue homeostasis. In this respect, efferocytosis, ie, the …
apoptotic debris in order to maintain tissue homeostasis. In this respect, efferocytosis, ie, the …
Involvement of aberrant regulation of epigenetic mechanisms in the pathogenesis of Parkinson's disease and epigenetic‐based therapies
…, F Taheri, D Rostami, N Farahani… - Journal of Cellular …, 2019 - Wiley Online Library
Parkinson's disease (PD) is known as a progressive neurodegenerative disorder associated
with the reduction of dopamine‐secreting neurons and the formation of Lewy bodies in the …
with the reduction of dopamine‐secreting neurons and the formation of Lewy bodies in the …
Circular RNAs: epigenetic regulators in cancerous and noncancerous skin diseases
A Abi, N Farahani, G Molavi, SM Gheibi Hayat - Cancer gene therapy, 2020 - nature.com
The most frequent kind of malignancy in the universe is skin cancer, which has been categorized
into non-melanoma and melanoma skin cancer. There are no complete information of …
into non-melanoma and melanoma skin cancer. There are no complete information of …
Recombinant protein expression in Escherichia coli (E. coli): what we need to know
SMG Hayat, N Farahani, B Golichenari… - Current …, 2018 - ingentaconnect.com
Background: Host, vector, and culture conditions (including cultivation media) are considered
among the three main elements contributing to a successful production of recombinant …
among the three main elements contributing to a successful production of recombinant …
LncRNAs as putative biomarkers and therapeutic targets for Parkinson's disease
…, F Taheri, SM Afshani, N Farahani… - Neurological …, 2021 - Springer
Parkinson’s disease (PD) is known as one of the most common degenerative disorders
related to the damage of the central nervous system (CNS). This brain disorder is also …
related to the damage of the central nervous system (CNS). This brain disorder is also …
Harnessing CRISPR/Cas9 technology in cardiovascular disease
H Rezaei, N Farahani, EZ Hosseingholi… - Trends in cardiovascular …, 2020 - Elsevier
The CRISPR/Cas9 system is a precisely targeted bacterial defense system, used to control
invading viruses. This technology has many potential applications including genetic changes …
invading viruses. This technology has many potential applications including genetic changes …
Autoantigen-specific immune tolerance in pathological and physiological cell death: Nanotechnology comes into view
A Tajbakhsh, N Farahani, SM Gheibihayat… - International …, 2021 - Elsevier
Apoptotic cells are tolerogenic and can present self-antigens in the absence of inflammation,
to antigen-presenting cells by the process of efferocytosis, resulting in anergy and …
to antigen-presenting cells by the process of efferocytosis, resulting in anergy and …
[HTML][HTML] Methylation pattern of ALX4 gene promoter as a potential biomarker for blood-based early detection of colorectal cancer
…, N Atapour, N Vatandoust, N Farahani… - Advanced biomedical …, 2015 - journals.lww.com
Background: To develop a non-invasive screening method for colorectal cancer, we evaluated
the methylation of ALX4 gene promoter in serum samples from patients with colorectal …
the methylation of ALX4 gene promoter in serum samples from patients with colorectal …
Gene delivery using lipoplexes and polyplexes: Principles, limitations and solutions
SMG Hayat, N Farahani, E Safdarian… - Critical Reviews™ in …, 2019 - dl.begellhouse.com
Gene therapy has attracted considerable attention for the treatment of genetic and acquired
diseases. Successful gene therapy occurs when the therapeutic genes penetrate targeted …
diseases. Successful gene therapy occurs when the therapeutic genes penetrate targeted …