Stat6 is known to drive macrophage M2 polarization. However, how macrophage polarization
is fine-tuned by Stat6 is poorly understood. Here, we find that Lys383 of Stat6 is acetylated …

Limited previous studies focused on the death and progression risk stratification of colorectal
cancer (CRC) lung metastasis patients. The aim of this study is to construct a nomogram …

Glycolysis plays a crucial role in reprogramming the metastatic tumor microenvironment. A
series of lncRNAs have been identified to function as oncogenic molecules by regulating …

Background Breast cancer stem cells (BCSCs) have been recently identified in breast carcinoma
as CD44 + CD24 - cells, which exclusively retain tumorigenic activity and display stem …

The existence of gastric cancer stem cells (CSCs) has not been definitively proven and
specific cell surface markers for identifying gastric CSCs have largely not been identified. Our …

α-synuclein (α-Syn) is a presynaptic enriched protein involved in the pathogenesis of Parkinson’s
disease. However, the physiological roles of α-Syn remain poorly understood. Recent …

Waned vaccine-induced immunity and emerging severe acute respiratory syndrome
coronavirus 2 variants with potential for immune escape pose a major threat to the coronavirus …

Systemic lupus erythematosus (SLE) is characterized by uncontrolled secretion of
autoantibodies by plasma cells. Although the functional importance of plasma cells and …

Background B cell-specific Moloney murine leukemia virus integration site 1 (Bmi-1) plays
an important role in regulating stemness in some kinds of cancer. However, the mechanisms …

With an increasing focus on phyto-remediation options for landfill leachate, it is important to
understand the responses of plant systems to landfill leachate stress. It is especially …