Hepatocellular carcinoma (HCC) is one of the most common cancers, with high mortality.
Chemotherapy is one of the main treatment options for HCC. However, the high toxicity and …

Colorectal cancer (CRC) remains a challenging and deadly disease with high tumor
microenvironment (TME) heterogeneity. Using an integrative multi-omics analysis and artificial …

Background Prostate cancer has become a serious threat to the life of patients. microRNAs
are small non-coding RNA molecules that regulate the growth and apoptosis of cells. We …

Although important progresses have been made in the diagnosis and treatment of bladder
cancer (BCa), the overall survival for patients with advanced BCa remains poor. It is …

Background: Higher tumor expression of CD44, a marker of cancer stem cells (CSCs), is
associated with poor overall survival (OS) in various cancers. However, the association …

Background Oxidative stress and inflammatory responses are critical factors in calcium
oxalate (CaOx) crystal-induced renal injury. Reactive oxygen species (ROS) are usually …

Objective This double-blind, placebo-controlled phase 3 study was designed to compare
efficacy and safety of abiraterone acetate + prednisone (abiraterone) to prednisone alone in …

Purpose Epidermoid tumors located in the cerebellopontine angle (CPA) are challenging
lesions because they tend to grow slowly in the subarachnoid cisterns around delicate …

Vitamin D has important biological functions including modulation of the immune system and
anti-cancer effects. There was no conclusive finding of the impact of serum vitamin D level …

Glycyrrhizic acid (GA) and Sirtuin3 (Sirt3) were both found to be involved in epilepsy (EP),
but their interaction was rarely studied. Herein, we aim to investigate the underlying …