Wnt/β-catenin signaling contributes to activation of normal and tumorigenic liver progenitor cells

…, DD Huang, L Tang, XN Kong, C Chen, SQ Liu, MC Wu… - Cancer research, 2008 - AACR
Adult hepatic progenitor (oval) cells are facultative stem cells in liver, which participate in a
range of human liver diseases, including hepatocellular carcinoma (HCC). However, the …

Endotoxin accumulation prevents carcinogen‐induced apoptosis and promotes liver tumorigenesis in rodents

LX Yu, HX Yan, Q Liu, W Yang, HP Wu, W Dong… - …, 2010 - Wiley Online Library
Increasing evidence suggests that the presence of endotoxemia is of substantial clinical
relevance to patients with cirrhosis, but it is unclear whether and how gut‐derived LPS amplifies …

Risk factors, patterns, and outcomes of late recurrence after liver resection for hepatocellular carcinoma: a multicenter study from China

…, H Wang, TH Chen, YY Zeng, C Li, MC Wu… - JAMA …, 2019 - jamanetwork.com
Importance Late recurrence (more than 2 years) after liver resection for hepatocellular
carcinoma (HCC) is generally considered as a multicentric tumor or a de novo cancer. Objective …

Partial hepatectomy vs. transcatheter arterial chemoembolization for resectable multiple hepatocellular carcinoma beyond Milan Criteria: a RCT

L Yin, H Li, AJ Li, WY Lau, Z Pan, ECH Lai, M Wu… - Journal of …, 2014 - Elsevier
Background & Aims The aim of this randomized comparative trial (RCT) is to compare partial
hepatectomy (PH) with transcatheter arterial chemoembolization (TACE) to treat patients …

Surgical treatment of hepatocellular carcinoma with portal vein tumor thrombus

…, N Li, WX Guo, J Xue, WY Lau, MC Wu… - Annals of surgical …, 2010 - Springer
Background The role of liver resection in patients with hepatocellular carcinoma (HCC)
accompanying with portal vein tumor thrombus (PVTT) remains controversial. This article aimed …

[HTML][HTML] Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma

…, Y Yang, W Wen, GS Lv, HL Zhang, H Wu… - Nature …, 2016 - nature.com
Hepatitis B virus (HBV) can integrate into the human genome, contributing to genomic
instability and hepatocarcinogenesis. Here by conducting high-throughput viral integration …

Association of Vimentin overexpression and hepatocellular carcinoma metastasis

…, JM Wen, W Wang, D Xie, M Huang, Y Wang, MC Wu… - Oncogene, 2004 - nature.com
The poor prognosis of hepatocellular carcinoma (HCC) has been associated with recurrence
and metastasis. Recently, we established a pair of HCC cell lines from a primary (H2-P) …

Prognostic significance of c‐myc and AIB1 amplification in hepatocellular carcinoma: A broad survey using high‐throughput tissue microarray

…, MC Wu, JST Sham, W Zhang, WQ Wu… - … Journal of the …, 2002 - Wiley Online Library
BACKGROUND Amplifications of 1q21, c‐myc at 8q24.1, and AIB1 at 20q12 are genetic
alterations that are detected frequently in hepatocellular carcinoma (HCC). The authors …

[PDF][PDF] Nuclear factor high‐mobility group box1 mediating the activation of Toll‐like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver …

…, YX Chang, QQ Tu, GS Feng, F Shen, MC Wu… - …, 2011 - Wiley Online Library
One of the challenges surrounding nonalcoholic fatty liver disease (NAFLD) is to discover
the mechanisms that underlie the initiation of it. The aim of the present study was to elucidate …

The role of microRNA expression pattern in human intrahepatic cholangiocarcinoma

…, L Li, DD Huang, J Ding, F Shen, WP Zhou, MC Wu… - Journal of …, 2009 - Elsevier
BACKGROUND/AIMS: MicroRNAs are a small non-coding family of genes involved in the
regulation of gene expression in a post-transcriptional manner and contribute to cell …