A pilot toxicology study of single-walled carbon nanotubes in a small sample of mice

ML Schipper, N Nakayama-Ratchford, CR Davis… - Nature …, 2008 - nature.com
Single-walled carbon nanotubes are currently under evaluation in biomedical applications,
including in vivo delivery 1 , 2 , 3 of drugs 4 , proteins, peptides 5 , 6 , 7 and nucleic acids 8 , …

Particle size, surface coating, and PEGylation influence the biodistribution of quantum dots in living mice

ML Schipper, G Iyer, AL Koh, Z Cheng, Y Ebenstein… - Small, 2009 - Wiley Online Library
This study evaluates the influence of particle size, PEGylation, and surface coating on the
quantitative biodistribution of near‐infrared‐emitting quantum dots (QDs) in mice. Polymer‐ or …

microPET-based biodistribution of quantum dots in living mice

ML Schipper, Z Cheng, SW Lee… - Journal of Nuclear …, 2007 - Soc Nuclear Med
… of 5.55 MBq in 25 pmol QD per animal—a QD dose that is commonly used by our group for
fluorescence imaging (Meike L. Schipper, Olivier Gheysens, unpublished data, August 2006). …

Targeted Microbubbles for Imaging Tumor Angiogenesis: Assessment of Whole-Body Biodistribution with Dynamic Micro-PET in Mice1

JK Willmann, Z Cheng, C Davis, AM Lutz, ML Schipper… - Radiology, 2008 - pubs.rsna.org
Purpose: To evaluate in vivo whole-body biodistribution of microbubbles (MBs) targeted to
tumor angiogenesis–related vascular endothelial growth factor (VEGF) receptor 2 (VEGFR2) …

Clinical value of parathyroid scintigraphy with technetium-99m methoxyisobutylisonitrile: discrepancies in clinical data and a systematic metaanalysis of the literature

…, TM Behr, A Bauhofer, C Franzius, ML Schipper… - World journal of …, 2004 - Springer
There is a considerable discrepancy in the literature concerning the sensitivity of parathyroid
scintigraphy (PS) with 99m Tc-MIBI. We therefore analyzed our own data and compared …

[HTML][HTML] Added value of gastrin receptor scintigraphy in comparison to somatostatin receptor scintigraphy in patients with carcinoids and other neuroendocrine …

…, A Bauhofer, A Rinke, ML Schipper… - Endocrine-Related …, 2006 - erc.bioscientifica.com
Gastrin receptor scintigraphy (GRS) is a new imaging method primarily developed for the
detection of metastases of medullary thyroid carcinoma (MTC). As gastrin-binding CCK 2 …

Evaluation of firefly luciferase bioluminescence mediated photodynamic toxicity in cancer cells

ML Schipper, MR Patel, SS Gambhir - Molecular Imaging and Biology, 2006 - Springer
Purpose This work investigated whether fLuc-catalyzed oxidation of d-luciferin generates
sufficient light to induce photodynamic toxicity in cancer cells. Procedures Light emission was …

Efficacy of 99mTc pertechnetate and 131I radioisotope therapy in sodium/iodide symporter (NIS)-expressing neuroendocrine tumors in vivo

ML Schipper, CGU Riese, S Seitz, A Weber… - European journal of …, 2007 - Springer
Purpose There is growing interest in the human sodium/iodide symporter (NIS) gene both as
a molecular imaging reporter gene and as a therapeutic gene. Here, we show the feasibility …

Radioiodide treatment after sodium iodide symporter gene transfer is a highly effective therapy in neuroendocrine tumor cells

ML Schipper, A Weber, M Béhé, R Göke, W Joba… - Cancer research, 2003 - AACR
This study evaluates the possibility of treating Bon1 and QGP pancreatic neuroendocrine
tumor cells with radioactive iodide ( 131 I) after stable transfection with the thyroid sodium …

[HTML][HTML] Tumor volume as a potential imaging-based risk-stratification factor in trimodality therapy for locally advanced non-small cell lung cancer

…, JD Murphy, ML Schipper, JS Donington, L Zhou… - Journal of thoracic …, 2011 - Elsevier
Introduction The role of trimodality therapy for locally advanced non-small cell lung cancer (NSCLC)
continues to be defined. We hypothesized that imaging parameters on pre- and …