Hepatitis B virus envelope L particles form hollow nanoparticles displaying a peptide that is
indispensable for liver-specific infection by hepatitis B virus in humans. Here we demonstrate …

Rat pancreatic AR42J cells possess exocrine and neuroendocrine properties. Activin A induces
morphological changes and converts them into neuron-like cells. In activin-treated cells, …

Cancer stem cells (CSCs) also known as cancer-initiating cells (CIC), are responsible for the
sustained and uncontrolled growth of malignant tumors and are proposed to play significant …

Cancer stem cells (CSCs) are capable of continuous proliferation and self-renewal and are
proposed to play significant roles in oncogenesis, tumor growth, metastasis and cancer …

Cancer-associated fibroblasts (CAFs) are one of the most prominent cell types in the stromal
compartment of the tumor microenvironment. CAFs support multiple aspects of cancer …

Cancer cells often secrete extracellular vesicles (EVs) that carry heat shock proteins (HSPs)
with roles in tumor progression. Oral squamous cell carcinoma (OSCC) belongs to head and …

… During a decade of research into CSCs development, Masaharu Seno’s group demonstrated
that the inflammatory microenvironment could drive stem cells into CSCs that exhibited self-…

Activin A and betacellulin (BTC) are thought to regulate differentiation of pancreatic β-cells
during development and regeneration of β-cells in adults. In the present study, we used …

Epithelial‐mesenchymal transition (EMT) facilitates migration and invasion of epithelial
tumor cells. Cripto‐1 (CR‐1), a member of the epidermal growth factor‐CFC protein family …

Cripto-1 (CR-1), an epidermal growth factor-CFC (EGF-CFC) family member, has a
demonstrated role in embryogenesis and mammary gland development and is overexpressed in …