The evolution of cancer surgery and future perspectives
L Wyld, RA Audisio, GJ Poston - Nature reviews Clinical oncology, 2015 - nature.com
Surgery is the oldest oncological discipline, dating back thousands of years. Prior to the
advent of anaesthesia and antisepsis 150 years ago, only the brave, desperate, or ill-advised …
advent of anaesthesia and antisepsis 150 years ago, only the brave, desperate, or ill-advised …
Quality of life versus length of life considerations in cancer patients: a systematic literature review
…, M Burton, S Walters, K Collins, L Wyld - Psycho …, 2019 - Wiley Online Library
Objective Patients with cancer face difficult decisions regarding treatment and the possibility
of trading quality of life (QoL) for length of life (LoL). Little information is available regarding …
of trading quality of life (QoL) for length of life (LoL). Little information is available regarding …
[HTML][HTML] Senescence and cancer: a review of clinical implications of senescence and senotherapies
L Wyld, I Bellantuono, T Tchkonia, J Morgan, O Turner… - Cancers, 2020 - mdpi.com
Cellular senescence is a key component of human aging that can be induced by a range of
stimuli, including DNA damage, cellular stress, telomere shortening, and the activation of …
stimuli, including DNA damage, cellular stress, telomere shortening, and the activation of …
Sentinel node biopsy using a magnetic tracer versus standard technique: the SentiMAG Multicentre Trial
…, A Kothari, K Zechmeister, D Brown, L Wyld… - Annals of surgical …, 2014 - Springer
Background The SentiMAG Multicentre Trial evaluated a new magnetic technique for
sentinel lymph node biopsy (SLNB) against the standard (radioisotope and blue dye or …
sentinel lymph node biopsy (SLNB) against the standard (radioisotope and blue dye or …
Surgery versus primary endocrine therapy for operable primary breast cancer in elderly women (70 years plus)
D Hind, L Wyld, C Beverley… - Cochrane Database of …, 2006 - cochranelibrary.com
Background Several studies have evaluated the clinical effectiveness of endocrine therapy
alone in women aged 70 years or over and who are fit for surgery. Objectives To identify and …
alone in women aged 70 years or over and who are fit for surgery. Objectives To identify and …
[HTML][HTML] Positron emission tomography (PET) and magnetic resonance imaging (MRI) for the assessment of axillary lymph node metastases in early breast cancer …
…, P Fitzgerald, D Papaioannou, L Wyld… - Health Technology …, 2011 - ncbi.nlm.nih.gov
BACKGROUND Breast cancer is the most common type of cancer in women. Evaluation of
axillary lymph node metastases is important for breast cancer staging and treatment planning. …
axillary lymph node metastases is important for breast cancer staging and treatment planning. …
[HTML][HTML] Oncoplastic Breast Consortium consensus conference on nipple-sparing mastectomy
…, V Lohsiriwat, T Kovacs, A Tansley, L Wyld… - Breast cancer research …, 2018 - Springer
Purpose Indications for nipple-sparing mastectomy (NSM) have broadened to include the risk
reducing setting and locally advanced tumors, which resulted in a dramatic increase in the …
reducing setting and locally advanced tumors, which resulted in a dramatic increase in the …
[HTML][HTML] Oncoplastic breast consortium recommendations for mastectomy and whole breast reconstruction in the setting of post-mastectomy radiation therapy
Aim Demand for nipple- and skin- sparing mastectomy (NSM/SSM) with immediate breast
reconstruction (BR) has increased at the same time as indications for post-mastectomy …
reconstruction (BR) has increased at the same time as indications for post-mastectomy …
[HTML][HTML] Bridging the Age Gap in breast cancer: Impact of chemotherapy on quality of life in older women with early breast cancer
…, MA Gosney, MQ Hatton, AM Thompson, L Wyld… - European Journal of …, 2021 - Elsevier
Introduction Older patients with early breast cancer (EBC) derive modest survival benefit
from chemotherapy but have increased toxicity risk. Data on the impact of chemotherapy for …
from chemotherapy but have increased toxicity risk. Data on the impact of chemotherapy for …
[HTML][HTML] Variation in treatment and survival of older patients with non-metastatic breast cancer in five European countries: a population-based cohort study from the …
…, E Van Eycken, S Siesling, J Broggio, L Wyld… - British journal of …, 2018 - nature.com
Background Older patients are poorly represented in breast cancer research and guidelines
do not provide evidence based recommendations for this specific group. We compared …
do not provide evidence based recommendations for this specific group. We compared …
