Insulin, IGF1, and IGF2 are the most studied insulin-like peptides (ILPs). These are evolutionary
conserved factors well known as key regulators of energy metabolism and growth, with …

In spite of strong evidence that the nucleus is a highly organized organelle, a consensus on
basic principles of the global nuclear architecture has not so far been achieved. The …

We have considered the possible effects of a diet containing genetically modified (GM) soybean
on mouse testis. This organ, in fact, is a well known bioindicator and it has already been …

Microbial-triggered inflammation protects against pathogens and yet can paradoxically
cause considerable secondary damage to host tissues that can result in tissue fibrosis and …

Breast cancer is the most common cancer in women worldwide. Understanding the biology
of this malignant disease is a prerequisite for selecting an appropriate treatment. Cell cycle …

Mesenchymal stromal cells (MSCs) are adult multipotent stem cells residing as pericytes in
various tissues and organs where they can differentiate into specialized cells to replace …

Master developmental pathways, such as Notch, Wnt, and Hedgehog, are signaling systems
that control proliferation, cell death, motility, migration, and stemness. These systems are …

The tumor microenvironment fuels tumorigenesis and induces the development of resistance
to anticancer drugs. A growing number of reports support that the tumor microenvironment …

Master developmental pathways, such as Notch, Wnt, and Hedgehog, are signaling systems
that control proliferation, cell death, motility, migration, and stemness. These systems are …

Obesity results from a chronic excessive accumulation of adipose tissue due to a long-term
imbalance between energy intake and expenditure. Available epidemiological and clinical …