Trajectories of α-fetoprotein and unresectable hepatocellular carcinoma outcomes receiving atezolizumab plus bevacizumab: a secondary analysis of IMbrave150 …

L Lu, P Zheng, Y Pan, S Huang, E Shao… - British Journal of …, 2023 - nature.com
Background α-fetoprotein (AFP) response has been demonstrated as a biomarker for unresectable
hepatocellular carcinoma (uHCC) patients receiving immunotherapy, but its definition …

[HTML][HTML] Prognostic nomogram to predict the overall survival of patients with early-onset colorectal cancer: a population-based analysis

J Wu, L Lu, H Chen, Y Lin, H Zhang, E Chen… - International Journal of …, 2021 - Springer
Purpose The present study aimed to identify independent clinicopathological and socio-economic
prognostic factors associated with overall survival of early-onset colorectal cancer (EO-…

[HTML][HTML] Hepatic resection versus transarterial chemoembolization for intermediate-stage hepatocellular carcinoma: a cohort study

L Lu, P Zheng, Z Wu, X Chen - Frontiers in oncology, 2021 - frontiersin.org
Background: The selection criterion for hepatic resection(HR) in intermediate-stage(IM)
hepatocellular carcinoma(HCC) is still controversial. We used real-world data to evaluate the …

[HTML][HTML] Trajectories of serum α-fetoprotein and intermediate-stage hepatocellular carcinoma outcomes after transarterial chemoembolization: A longitudinal …

L Lu, L Shen, Z Wu, Y Shi, P Hou, Z Xue, C Lin… - …, 2022 - thelancet.com
Background α-fetoprotein (AFP) response has been proven a key tumor marker for
hepatocellular carcinoma (HCC), but its definition remains controversial. This study aims to …

[HTML][HTML] The aMAP Score is an independent risk factor for intermediate-stage hepatocellular carcinoma: a large retrospective cohort study

Y Chen, Y Shi, L Lu, X Wang, Q Lin, Y Lin… - Journal of …, 2023 - ncbi.nlm.nih.gov
Background: A less effective nomogram for patients with intermediate-stage hepatocellular
carcinoma (HCC) to predict overall survival (OS) is available. This study aimed to investigate …

Gut microbiota and sunitinib-induced diarrhea in metastatic renal cell carcinoma: a pilot study

Z Su, L Lu, F Chen, J Chen, X Chen - Cancer Management and …, 2021 - Taylor & Francis
Introduction Sunitinib-induced diarrhea seriously affects the prognosis of patients with
metastatic renal cell carcinoma (mRCC) and reduces their quality of life. We aim to explore and …

[HTML][HTML] Association of antibiotic exposure with the mortality in metastatic colorectal cancer patients treated with bevacizumab-containing chemotherapy: A hospital …

L Lu, T Zhuang, E Shao, Y Liu, H He, Z Shu, Y Huang… - PLoS …, 2019 - journals.plos.org
Background Preclinical studies showed that antibiotic exposure played a role in clinical
outcomes in patients with chemotherapy via modulation of microbiota. However, it remains …

[HTML][HTML] Case report: Long response to PD-1 blockade after failure of trastuzumab plus chemotherapy in advanced Epstein-Barr virus-associated gastric cancer

Y Pan, L Lu, H Liu, D Chen, N Han, R Yao… - Frontiers in …, 2022 - frontiersin.org
Background Trastuzumab-containing chemotherapy is the first-line treatment for advanced
gastric cancer (GC) with HER2 positive. Although PD-1 inhibitors significantly improved the …

Association between platelet count and hepatocellular carcinoma overall survival: a large retrospective cohort study

L Lu, Z Su, P Zheng, Z Wu, Y Zhang, H He, J Liu… - BMJ open, 2020 - bmjopen.bmj.com
Objectives To explore the non-linear relationship between platelet count (PLT) and hepatocellular
carcinoma (HCC) overall survival (OS). Setting The study was done in Sun Yat-sen …

Prognosis of Patients with Hepatocellular Carcinoma Treated with Transarterial Chemoembolization (MC-hccAI 001): Development and Validation of the ALFP Score

…, Y Shi, Y Chen, S Gao, J Chen, L Liu, L Lu… - Journal of …, 2023 - Taylor & Francis
Background Transarterial chemoembolization (TACE) is the recommended first-line treatment
for intermediate-stage Hepatocellular carcinoma (HCC) patients. However, predicting the …