Chemotherapy has been widely used in treatment of cancer, both as systemic therapy and
as part of local treatment. Unfortunately, many kinds of cancer are still refractory to …

Recent advances in systemic and locoregional treatments for patients with unresectable or
advanced hepatocellular carcinoma (HCC) have resulted in improved response rates. This …

CONTEXT: Laparoscopic nephroureterectomy (LNU) has increasingly been used as a
minimally invasive alternative to open nephroureterectomy (ONU), but studies comparing the …

Background: Primary liver cancer, around 90% are hepatocellular carcinoma in China, is
the fourth most common malignancy and the second leading cause of tumor-related death, …

Colorectal cancer (CRC) is among the most common malignancies with limited treatments
other than surgery. The tumor microenvironment (TME) profiling enables the discovery of …

Background & Aims The tumour microenvironment (TME) is a crucial mediator of cancer
progression and therapeutic outcome. The TME subtype correlates with patient response to …

Tumour cells primarily utilize aerobic glycolysis for energy production, a phenomenon known
as the Warburg effect. Its mechanism is not well understood. The tumour suppressor gene …

Several studies show that the immunosuppressive drugs targeting the interleukin-6 (IL-6)
receptor, including tocilizumab, ameliorate lethal inflammatory responses in COVID-19 patients …

The increasing incidence of hepatocellular carcinoma (HCC) is of great concern not only in
the United States but throughout the world. Although sorafenib, a multikinase inhibitor with …

Epidemiological studies strongly suggest that chronic psychological stress promotes
tumorigenesis. However, its direct link in vivo and the underlying mechanisms that cause this …