[HTML][HTML] miR-9 functions as a tumor suppressor in ovarian serous carcinoma by targeting TLN1

H Tang, L Yao, X Tao, Y Yu… - International …, 2013 - spandidos-publications.com
microRNAs (miRNAs) are important regulators of gene expression during tumorigenesis.
The downregulation of microRNA-9 (miR-9) has been reported in ovarian serous carcinoma (…

A general route to sulfones via insertion of sulfur dioxide promoted by cobalt oxide

D Zheng, M Chen, L Yao, J Wu - Organic Chemistry Frontiers, 2016 - pubs.rsc.org
A cobalt-promoted coupling reaction of triethoxysilanes, sulfur dioxide, and electrophiles is
developed. Benzylic, allylic or alkyl bromides are all efficient as electrophiles in this …

Fuzuloparib maintenance therapy in patients with platinum-sensitive, recurrent ovarian carcinoma (FZOCUS-2): a multicenter, randomized, double-blind, placebo …

…, X Guo, S Yao, X Wan, H Zhou, L Yao… - Journal of Clinical …, 2022 - ingentaconnect.com
PURPOSE This phase III trial aimed to explore the efficacy and safety of fuzuloparib (formerly
fluzoparib) versus placebo as a maintenance treatment after response to second- or later-…

BTB and CNC homology 1 (Bach1) promotes human ovarian cancer cell metastasis by HMGA2-mediated epithelial-mesenchymal transition

…, Y Zhang, C Niu, J Guo, J Li, X Wei, M Jia, X Zhi, L Yao… - Cancer Letters, 2019 - Elsevier
Transcriptional factor BTB and CNC homology 1 (Bach1) has been linked to tumor progression
and metastasis, but the mechanisms underlying the effects of Bach1 on tumor growth and …

[HTML][HTML] The proliferation, apoptosis, invasion of endothelial-like epithelial ovarian cancer cells induced by hypoxia

P Zhu, Y Ning, L Yao, M Chen, C Xu - Journal of Experimental & Clinical …, 2010 - Springer
Background Epithelial ovarian cancer is one of the most malignant cancers in women
because metastasis occurs in the most of patients by the time of diagnosis. Cancer cells have …

[HTML][HTML] Pan-cancer analyses and molecular subtypes based on the cancer-associated fibroblast landscape and tumor microenvironment infiltration characterization …

R Zou, Q Jiang, T Jin, M Chen, L Yao… - Frontiers in …, 2022 - frontiersin.org
Background Cancer-associated fibroblasts (CAFs) are essential components of the tumor
microenvironment (TME). These cells play a supportive role throughout cancer progression. …

Synthesis of sulfonated naphthols via C–H bond functionalization with the insertion of sulfur dioxide

K Zhou, M Chen, L Yao, J Wu - Organic Chemistry Frontiers, 2018 - pubs.rsc.org
A three-component reaction of naphthols, sulfur dioxide, and aryldiazonium tetrafluoroborates
catalyzed by iron(III) chloride through a radical process via direct C–H functionalization is …

An unexpected reaction of 2-alkynylaryldiazonium tetrafluoroborate with sulfur dioxide

Y Luo, X Pan, C Chen, L Yao, J Wu - Chemical communications, 2015 - pubs.rsc.org
An unexpected result from the reaction of 2-alkynylaryldiazonium tetrafluoroborate with sulfur
dioxide is described. In the presence of morpholin-4-amine, this transformation catalyzed …

Depletion of UBE2C reduces ovarian cancer malignancy and reverses cisplatin resistance via downregulating CDK1

…, X Shen, C Chen, L Yuan, X Dong, C Zhu, L Yao… - Biochemical and …, 2020 - Elsevier
Ovarian cancer is the most lethal gynecological malignancy, but the mechanisms of ovarian
cancer progression and cisplatin resistance remain unclear. Emerging evidence suggested …

[HTML][HTML] Deep learning for the ovarian lesion localization and discrimination between borderline and malignant ovarian tumors based on routine MR imaging

Y Wang, H Zhang, T Wang, L Yao, G Zhang, X Liu… - Scientific Reports, 2023 - nature.com
To establish a deep learning (DL) model in differentiating borderline ovarian tumor (BOT) from
epithelial ovarian cancer (EOC) on conventional MR imaging. We retrospectively enrolled …