User profiles for Lele Song

Lele Song

University of Pennsylvania
Verified email at pennmedicine.upenn.edu
Cited by 512

[HTML][HTML] Loss of Wwox drives metastasis in triple-negative breast cancer by JAK2/STAT3 axis

R Chang, L Song, Y Xu, Y Wu, C Dai, X Wang… - Nature …, 2018 - nature.com
Loss of WW domain-containing oxidoreductase (Wwox) expression has been observed in
breast cancer (BC). However, its regulatory effects are largely unknown, especially in triple-…

[HTML][HTML] The performance of the SEPT9 gene methylation assay and a comparison with other CRC screening tests: A meta-analysis

L Song, J Jia, X Peng, W Xiao, Y Li - Scientific reports, 2017 - nature.com
Lele Song and Yuemin Li conceived and designed the study. Lele Song, Jia Jia and Xiumei
Peng performed the literature search, collected and analyzed data. Lele Song made tables, …

[HTML][HTML] Loss of Scribble confers cisplatin resistance during NSCLC chemotherapy via Nox2/ROS and Nrf2/PD-L1 signaling

N Wang, L Song, Y Xu, L Zhang, Y Wu, J Guo, W Ji… - …, 2019 - thelancet.com
Background Cisplatin resistance remains a major clinical obstacle to the successful treatment
of non-small cell lung cancer (NSCLC). Scribble contributes to ROS-induced inflammation …

SEPT9: a specific circulating biomarker for colorectal cancer

L Song, Y Li - advances in clinical chemistry, 2015 - Elsevier
SEPT9 gene methylation has been implicated as a biomarker for colorectal cancer (CRC)
for more than 10 years and has been used clinically for more than 6 years. Studies have …

A systematic review of the performance of the SEPT9 gene methylation assay in colorectal cancer screening, monitoring, diagnosis and prognosis

L Song, H Yu, J Jia, Y Li - Cancer Biomarkers, 2017 - content.iospress.com
… 1Lele Song and Haotian Yu contributed equally to this work. … Lele Song, is currently an
employee of BioChain (Beijing) Science and Technology, Inc. BioChain is a collaborator of …

Development of small molecules targeting the Wnt signaling pathway in cancer stem cells for the treatment of colorectal cancer

L Song, Y Li, B He, Y Gong - Clinical colorectal cancer, 2015 - Elsevier
Colorectal cancer (CRC) was ranked third in morbidity and mortality in the United States in
2013. Although substantial progress has been made in surgical techniques and …

Performance of a second‐generation methylated SEPT9 test in detecting colorectal neoplasm

…, Y He, X Han, J Hang, J Zhang, L Song… - Journal of …, 2015 - Wiley Online Library
Background and Aim Screening and early detection reduces mortality due to colorectal
cancer ( CRC ). Methylated Septin 9 ( SEPT9 ) is a new blood‐based biomarker for CRC . We …

[PDF][PDF] Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer

L Song, X Yao, H Li, B Peng, AP Boka, Y Liu, G Chen… - Molecular cell, 2022 - cell.com
Growing evidence suggests prevalence of transcriptional condensates on chromatin, yet
their mechanisms of formation and functional significance remain largely unclear. In human …

Ultrafast Fabrication of Large‐Area Colloidal Crystal Micropatterns via Self‐Assembly and Transfer Printing

…, L Chen, Y Ma, D Weng, Z Li, L Song… - Advanced Functional …, 2022 - Wiley Online Library
Colloidal crystals have brought the promise of revolution to modern engineering, yet
commonly used fabrication technologies are still limited by the small preparation area, time‐…

[HTML][HTML] Detection of colorectal cancer using a simplified SEPT9 gene methylation assay is a reliable method for opportunistic screening

…, S Li, Q Wu, G Wang, J Sheng, J Wang, L Song… - The Journal of Molecular …, 2016 - Elsevier
SEPT9 gene methylation was validated as a biomarker for colorectal cancer (CRC) for >10
years and available as the Epi proColon test as an aid in CRC detection for >6 years. It was …