Tumors are not only aggregates of malignant cells but also well-organized complex
ecosystems. The immunological components within tumors, termed the tumor immune …

The molecular heterogeneity and distinct features of HER2-low breast cancers, particularly
in the Chinese population, are not well understood, limiting its precise management in the …

Molecular profiling guides precision treatment of breast cancer; however, Asian patients are
underrepresented in publicly available large-scale studies. We established a …

The concept of antibody–drug conjugations (ADCs) can be tracked back to the early 20th
century when the renowned immunologist, Paul Ehrlich, proposed the idea of a “magic bullet”, …

The associated article reports multiomic analysis of breast cancers, where we provided a
unique public resource that contributes novel insights into the breast cancer, holding promise …

Cancer has been a major cause of death in China. Among oncologists, the concept of precision
cancer medicine has been universally acknowledged. Precision cancer medicine aims …

Background: Anti-HER2 targeted therapy has achieved a series of breakthroughs. However,
the current treatment strategy regarding HER2-positive breast cancer remains …

Background: The emergence of anti-HER2 antibody–drug conjugates (ADCs) gave rise to
the concept of HER2-low breast cancer (BC). HER2-low BC, which refers to a subgroup of …

The canonical approach to video-and-language learning (eg, video question answering)
dictates a neural model to learn from offline-extracted dense video features from vision models …

Existing methods for vision-and-language learning typically require designing task-specific
architectures and objectives for each task. For example, a multi-label answer classifier for …