User profiles for Lei You

Lei You

the University of Texas Health Science Center at Houston
Verified email at uth.tmc.edu
Cited by 561

Recent advances in supramolecular analytical chemistry using optical sensing

L You, D Zha, EV Anslyn - Chemical reviews, 2015 - ACS Publications
The field of supramolecular chemistry has been flourishing since J.-M. Lehn, DJ Cram, and
CJ Pedersen were awarded the 1987 Nobel Prize in Chemistry. By Prof. Lehn’s definition, 1 “…

Dynamic multi-component covalent assembly for the reversible binding of secondary alcohols and chirality sensing

L You, JS Berman, EV Anslyn - Nature chemistry, 2011 - nature.com
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Detection of Covid-19 in children in early January 2020 in Wuhan, China

…, S Shu, L Chen, L Liang, J Zhou, L You… - … England Journal of …, 2020 - Mass Medical Soc
Children with Covid-19 in Wuhan, China A retrospective analysis of routine surveillance
data involving children hospitalized in central Wuhan, China, for acute lower respiratory …

[HTML][HTML] Generative adversarial networks and its applications in biomedical informatics

L Lan, L You, Z Zhang, Z Fan, W Zhao, N Zeng… - Frontiers in public …, 2020 - frontiersin.org
The basic Generative Adversarial Networks (GAN) model is composed of the input vector,
generator, and discriminator. Among them, the generator and discriminator are implicit …

Early screening and diagnosis strategies of pancreatic cancer: a comprehensive review

…, R Xu, C Wang, J Qiu, B Ren, L You - Cancer …, 2021 - Wiley Online Library
Pancreatic cancer is a highly malignant digestive system tumor with a poor prognosis. Most
pancreatic cancer patients are diagnosed at an advanced stage or even metastasis due to its …

[HTML][HTML] Tumor microenvironment participates in metastasis of pancreatic cancer

B Ren, M Cui, G Yang, H Wang, M Feng, L You… - Molecular cancer, 2018 - Springer
Pancreatic cancer is a deadly disease with high mortality due to difficulties in its early
diagnosis and metastasis. The tumor microenvironment induced by interactions between …

[HTML][HTML] Targeting hypoxic tumor microenvironment in pancreatic cancer

…, W Zhou, J Qiu, G Chen, W Luo, F Zhao, L You… - Journal of hematology & …, 2021 - Springer
Attributable to its late diagnosis, early metastasis, and poor prognosis, pancreatic cancer
remains one of the most lethal diseases worldwide. Unlike other solid tumors, pancreatic …

Advances in the epidemiology of pancreatic cancer: Trends, risk factors, screening, and prognosis

J Cai, H Chen, M Lu, Y Zhang, B Lu, L You, T Zhang… - Cancer letters, 2021 - Elsevier
Pancreatic cancer is a malignancy with poor prognosis and high mortality. The recent
increase in pancreatic cancer incidence and mortality has resulted in an increased number of …

[HTML][HTML] 5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers

W Li, X Zhang, X Lu, L You, Y Song, Z Luo, J Zhang… - Cell research, 2017 - nature.com
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PD-1/PD-L1 and immunotherapy for pancreatic cancer

…, G Xiong, Z Cao, G Yang, S Zheng, X Song, L You… - Cancer letters, 2017 - Elsevier
Therapy that targets programmed death 1 or programmed death 1 ligand 1 (PD-1/PD-L1),
which are known as immune checkpoints, has been recently rapidly developing as …