User profiles for Laurent A. Bentolila

Laurent A. Bentolila

Dept of Chemistry & Biochemistry, California NanoSystems Institute, UCLA
Verified email at chem.ucla.edu
Cited by 15057

Quantum dots for live cells, in vivo imaging, and diagnostics

X Michalet, FF Pinaud, LA Bentolila, JM Tsay, S Doose… - science, 2005 - science.org
Research on fluorescent semiconductor nanocrystals (also known as quantum dots or qdots)
has evolved over the past two decades from electronic materials science to biological …

Deep learning enables cross-modality super-resolution in fluorescence microscopy

…, Y Jin, Z Wei, R Gao, H Günaydın, LA Bentolila… - Nature …, 2019 - nature.com
We present deep-learning-enabled super-resolution across different fluorescence
microscopy modalities. This data-driven approach does not require numerical modeling of the …

Particle size, surface coating, and PEGylation influence the biodistribution of quantum dots in living mice

…, Y Ebenstein, A Aharoni, S Keren, LA Bentolila… - Small, 2009 - Wiley Online Library
This study evaluates the influence of particle size, PEGylation, and surface coating on the
quantitative biodistribution of near‐infrared‐emitting quantum dots (QDs) in mice. Polymer‐ or …

Advances in fluorescence imaging with quantum dot bio-probes

F Pinaud, X Michalet, LA Bentolila, JM Tsay, S Doose… - Biomaterials, 2006 - Elsevier
After much effort in surface chemistry development and optimization by several groups,
fluorescent semiconductor nanocrystals probes, also known as quantum dots or qdots, are now …

Fluorescent imaging of single nanoparticles and viruses on a smart phone

…, D Tseng, SJ Ki, Z Wan, Z Göröcs, LA Bentolila… - ACS …, 2013 - ACS Publications
Optical imaging of nanoscale objects, whether it is based on scattering or fluorescence, is a
challenging task due to reduced detection signal-to-noise ratio and contrast at …

WNT10B/β‐catenin signalling induces HMGA2 and proliferation in metastatic triple‐negative breast cancer

…, MS Lesniak, R Wolsky, LA Bentolila… - EMBO molecular …, 2013 - embopress.org
Wnt/β‐catenin signalling has been suggested to be active in basal‐like breast cancer.
However, in highly aggressive metastatic triple‐negative breast cancers (TNBC) the role of β‐…

Quantum dots for in vivo small-animal imaging

LA Bentolila, Y Ebenstein, S Weiss - Journal of nuclear medicine, 2009 - Soc Nuclear Med
Nanotechnology is poised to transform research, prevention, and treatment of cancer through
the development of novel diagnostic imaging methods and targeted therapies. In particular…

Three-dimensional virtual refocusing of fluorescence microscopy images using deep learning

…, H Wang, Y Luo, E Ben-David, LA Bentolila… - Nature …, 2019 - nature.com
We demonstrate that a deep neural network can be trained to virtually refocus a two-dimensional
fluorescence image onto user-defined three-dimensional (3D) surfaces within the …

[PDF][PDF] Aster proteins facilitate nonvesicular plasma membrane to ER cholesterol transport in mammalian cells

…, SD Lee, C He, C Hong, H Jiang, LA Bentolila… - Cell, 2018 - cell.com
The mechanisms underlying sterol transport in mammalian cells are poorly understood. In
particular, how cholesterol internalized from HDL is made available to the cell for storage or …

microPET-based biodistribution of quantum dots in living mice

…, Z Cheng, SW Lee, LA Bentolila… - Journal of Nuclear …, 2007 - Soc Nuclear Med
This study evaluates the quantitative biodistribution of commercially available CdSe quantum
dots (QD) in mice. Methods: 64 Cu-Labeled 800- or 525-nm emission wavelength QD (21- …