Fulvestrant 500 mg versus anastrozole 1 mg for hormone receptor-positive advanced breast cancer (FALCON): an international, randomised, double-blind, phase 3 …

…, Y Shparyk, S Cardona-Huerta, KL Cheung… - The Lancet, 2016 - thelancet.com
Background Aromatase inhibitors are a standard of care for hormone receptor-positive locally
advanced or metastatic breast cancer. We investigated whether the selective oestrogen …

Fulvestrant plus anastrozole or placebo versus exemestane alone after progression on non-steroidal aromatase inhibitors in postmenopausal patients with hormone …

…, YH Im, JP Braybrooke, AM Brunt, KL Cheung… - The Lancet …, 2013 - thelancet.com
Background The optimum endocrine treatment for postmenopausal women with advanced
hormone-receptor-positive breast cancer that has progressed on non-steroidal aromatase …

Concepts of seroma formation and prevention in breast cancer surgery

…, AA Ayantunde, KL Cheung - ANZ Journal of surgery, 2006 - Wiley Online Library
Background: Seroma formation is the commonest early sequel to breast cancer surgery
especially when axillary dissection is undertaken. It is associated with significant morbidity and …

Updated recommendations regarding the management of older patients with breast cancer: a joint paper from the European Society of Breast Cancer Specialists …

…, IH Kunkler, MJ Cardoso, KL Cheung… - The Lancet …, 2021 - thelancet.com
Breast cancer is increasingly prevalent in older adults and is a substantial part of routine
oncology practice. However, management of breast cancer in this population is challenging …

Cyclin E overexpression sensitizes triple-negative breast cancer to Wee1 kinase inhibition

…, KW Evans, M Yi, DC Ellis, KL Cheung… - Clinical Cancer …, 2018 - AACR
Purpose: Poor prognosis in triple-negative breast cancer (TNBC) is due to an aggressive
phenotype and lack of biomarker-driven targeted therapies. Overexpression of cyclin E and …

Priorities for the global advancement of care for older adults with cancer: an update of the International Society of Geriatric Oncology Priorities Initiative

…, E Brain, B Canin, MN Cherian, KL Cheung… - The Lancet …, 2021 - thelancet.com
In 2011, the International Society of Geriatric Oncology (SIOG) published the SIOG 10 Priorities
Initiative, which defined top priorities for the improvement of the care of older adults with …

Adapting care for older cancer patients during the COVID-19 pandemic: Recommendations from the International Society of Geriatric Oncology (SIOG) COVID-19 …

…, A O'Donovan, RA Audisio, KL Cheung… - Journal of geriatric …, 2020 - Elsevier
The COVID-19 pandemic poses a barrier to equal and evidence-based management of cancer
in older adults. The International Society of Geriatric Oncology (SIOG) formed a panel of …

Interruption and non-adherence to long-term adjuvant hormone therapy is associated with adverse survival outcome of breast cancer women-an Asian population …

KP Hsieh, LC Chen, KL Cheung, CS Chang… - PLoS One, 2014 - journals.plos.org
This study aimed to evaluate the survival rate of women with breast cancer (BC) comparing
persistence versus interruption and adherence versus non-adherence to adjuvant hormonal …

Invasive lobular breast cancer as a distinct disease: implications for therapeutic strategy

J Luveta, RM Parks, DM Heery, KL Cheung… - Oncology and …, 2020 - Springer
Invasive lobular carcinoma comprises 10–15% of all breast cancers and is increasingly
recognised as a distinct and understudied disease compared with the predominant histological …

Cytoplasmic cyclin E predicts recurrence in patients with breast cancer

…, ML Bondy, PA Thompson, KL Cheung… - Clinical Cancer …, 2017 - AACR
Purpose: Low molecular weight cyclin E (LMW-E) detected by Western blot analysis predicts
for reduced breast cancer survival; however, it is impractical for clinical use. LMW-E lacks a …