Next‐generation sequencing ( NGS ) of tumor tissue (ie, clinical sequencing) can guide
clinical management by providing information about actionable gene aberrations that have …

Purpose Inhibition of transforming growth factor-beta receptor I (TGF-beta RI)-mediated
signaling pathways blocks tumor growth and metastases in nonclinical studies. Galunisertib (…

Background To promote precision oncology in clinical practice, the Japanese Society of
Medical Oncology, the Japanese Society of Clinical Oncology, and the Japanese Cancer …

Introduction Ciliated muconodular papillary tumors (CMPTs) are recently characterized, rare
peripheral nodules of the lung. These small tumors are histologically comprised of a …

Two cases of pediatric lung cancer (in 23-month-old and 6-year-old boys) resulting from
mother-to-infant transmission of uterine cervical tumors were incidentally detected during …

… Kuniko Sunami and Hideaki Bando contributed equally to … Kuniko Sunami and Hideaki
Bando contributed equally to this … Kuniko Sunami and Hideaki Bando contributed equally to this …

Previous clinical trials indicate that 10%–25% of patients received genomically matched
therapy after comprehensive genomic profiling (CGP) tests. However, the clinical utility of CGP …

… Kuniko Sunami and Yoichi Naito contributed equally to this work. … Kuniko Sunami received
research funds from Sysmex. Yoichi Naito received lecture fees from Chugai, Pfizer, Eli Lilly, …

Background Since June 2019, cancer genomic profiling (CGP) tests have been reimbursed
by the National Health Insurance system in Japan, with restrictions for government-…

The year 2019 was considered to be the first year of cancer genome medicine in Japan,
with three gene‐panel tests using next‐generation sequencing (NGS) techniques being …