The purpose of this study was to determine the safety, distribution, internal dosimetry, and
initial human epidermal growth factor receptor 2 (HER2)–positive tumor images of 64 Cu-…

Insulinoma-associated protein 1 (INSM1) is expressed exclusively in embryonic developing
neuroendocrine (NE) tissues. INSM1 gene expression is specific for small-cell lung cancer (…

Among the various types of oligosaccharide structures, asparagine-linked oligosaccharides
(N-glycans) are the most prominent in terms of diversity and complexity. In particular, N-…

Introduction Notch signaling plays a key role in a wide variety of human neoplasms, and it
can be either oncogenic or anti-proliferative. Moreover, Notch function in regulating cancer is …

We have previously established a concept of developing exogenic pancreas in a genetically
modified pig fetus with an apancreatic trait, thereby proposing the possibility of in vivo …

Our recent work suggested that intranasal coadministration with the cell-penetrating peptide
(CPP) penetratin increased the brain distribution of the peptide drug insulin. The present …

This paper proposes a novel modular equalization architecture for series-connected electric
double-layer capacitor (EDLC) modules, each consisting of multiple cells connected in …

Background Small cell lung carcinoma ( SCLC ) is characterized by a high rate of relapse and
failure of chemotherapy because of the emergence of drug resistant cells. N otch signaling …

Molecular imaging technique by use of positron emission tomography (PET) is a noninvasive
tool that allows one to quantitatively analyze the function of endogenous molecules and …

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited
kidney disease, manifesting as the progressive development of fluid-filled renal cysts. In …