Molecular theranostics: a primer for the imaging professional
DY Lee, KCP Li - American Journal of Roentgenology, 2011 - Am Roentgen Ray Soc
OBJECTIVE. A theranostic system integrates some form of diagnostic testing to determine
the presence of a molecular target for which a specific drug is intended. Molecular imaging …
the presence of a molecular target for which a specific drug is intended. Molecular imaging …
Detection of tumor angiogenesis in vivo by αvβ3-targeted magnetic resonance imaging
…, MR Kazemi, LM Nevin, MD Bednarski, KCP Li - Nature medicine, 1998 - nature.com
Angiogenesis, the formation of new blood vessels, is a requirement for malignant tumor
growth and metastasis 1–3 . In the absence of angiogenesis, local tumor expansion is …
growth and metastasis 1–3 . In the absence of angiogenesis, local tumor expansion is …
Molecular imaging applications in nanomedicine
KCP Li, SD Pandit, S Guccione, MD Bednarski - Biomedical Microdevices, 2004 - Springer
The purpose of this article is to explore how molecular imaging techniques can be used as
useful adjunts in the development of “nanomedicine” and in personalizing treatment of …
useful adjunts in the development of “nanomedicine” and in personalizing treatment of …
Pulsed-high intensity focused ultrasound and low temperature–sensitive liposomes for enhanced targeted drug delivery and antitumor effect
…, M Angstadt, M Bur, J Poff, J Xie, SK Libutti, KCP Li… - Clinical cancer …, 2007 - AACR
Purpose: To determine if pulsed-high intensity focused ultrasound (HIFU) could effectively
serve as a source of hyperthermia with thermosensitive liposomes to enhance delivery and …
serve as a source of hyperthermia with thermosensitive liposomes to enhance delivery and …
In vivo monitoring of tumor angiogenesis with MR imaging
RC Brasch, KCP Li, JE Husband, MT Keogan… - Academic radiology, 2000 - Elsevier
Magnetic resonance (MR) imaging is a widely employed diagnostic method for the evaluation
of patients with tumors. This method is noted for its remarkable soft-tissue definition, …
of patients with tumors. This method is noted for its remarkable soft-tissue definition, …
Delivery of systemic chemotherapeutic agent to tumors by using focused ultrasound: study in a murine model
PURPOSE: To quantitatively determine the delivery of systemic liposomal doxorubicin to
tumors treated with pulsed high-intensity focused ultrasound and to study the mechanism …
tumors treated with pulsed high-intensity focused ultrasound and to study the mechanism …
Delivery of liposomal doxorubicin (Doxil) in a breast cancer tumor model: investigation of potential enhancement by pulsed-high intensity focused ultrasound exposure
…, J Quijano, J Xie, F Hunter, S Dromi, KCP Li - Academic radiology, 2006 - Elsevier
RATIONALE AND OBJECTIVES: To investigate the potential of using pulsed high-intensity
focused ultrasound (HIFU) exposures to enhance the delivery, and hence therapeutic effect of …
focused ultrasound (HIFU) exposures to enhance the delivery, and hence therapeutic effect of …
Gadolinium-DTPA-enhanced magnetic resonance imaging of musculoskeletal infectious processes
KL Hopkins, KCP Li, G Bergman - Skeletal radiology, 1995 - Springer
The purpose of this study was to assess whether gadolinium-enhanced magnetic resonance
imaging (MRI) provides diagnostic information beyond that given by nonenhanced imaging …
imaging (MRI) provides diagnostic information beyond that given by nonenhanced imaging …
Pulsed High-Intensity Focused Ultrasound Enhances Thrombolysis in an in Vitro Model1
Purpose: To evaluate the use of pulsed high-intensity focused ultrasound exposures to improve
tissue plasminogen activator (tPA)-mediated thrombolysis in an in vitro model. Materials …
tissue plasminogen activator (tPA)-mediated thrombolysis in an in vitro model. Materials …
Pulsed high-intensity focused ultrasound enhances uptake of radiolabeled monoclonal antibody to human epidermoid tumor in nude mice
…, JA Carrasquillo, I Pastan, KCP Li… - Journal of Nuclear …, 2008 - Soc Nuclear Med
The aim of this study was to determine if pulsed high-intensity focused ultrasound (HIFU)
exposures could enhance tumor uptake of 111 In-MX-B3, a murine IgG1κ monoclonal antibody …
exposures could enhance tumor uptake of 111 In-MX-B3, a murine IgG1κ monoclonal antibody …