ATP-sensitive K + (K ATP ) channels play a crucial role in coupling metabolic energy to the
membrane potential of cells. We have isolated a cDNA encoding a novel member (uK ATP -1…

Lipoproteins in Escherichia coli are anchored to the periplasmic side of either the inner or the
outer membrane by a lipid moiety that is covalently attached to the amino-terminal cysteine …

Removal of the fucose residue from the N‐glycans of the Fc portion of immunoglobulin G (IgG)
results in a dramatic enhancement of antibody‐dependent cellular cytotoxicity (ADCC) …

Antibody-dependent cellular cytotoxicity (ADCC) is considered to be an important therapeutic
function for clinical efficacy of monoclonal antibodies. Recent studies have revealed two …

Objectives The Japanese Orthopaedic Association (JOA) score is widely used to assess the
severity of clinical symptoms in patients with cervical compressive myelopathy, particularly …

Somatostatin exerts diverse effects in various tissues upon binding its specific membrane
receptors. Recently, we have cloned three different somatostatin receptor subtypes. Here we …

Purpose The Oswestry Disability Index (ODI) is one of the most common scoring systems
used for patients with low back pain (LBP). Although the normative score of the ODI was …

Importance The optimal management for acute traumatic cervical spinal cord injury (SCI) is
unknown. Objective To determine whether early surgical decompression results in better …

Escherichia coli lipoproteins are anchored to the inner or outer membrane depending on
the residue at position 2. Aspartate at this position makes lipoproteins specific to the inner …

Engineered cysteine residues are particularly convenient for site-specific conjugation of
antibody–drug conjugates (ADC), because no cell engineering and additives are required. …