Capsular contracture is the most common complication following implant based breast
surgery and is one of the most common reasons for reoperation. Therefore, it is important to try …

Purpose: Rho family members are small GTPases that are known to regulate malignant
transformation and motility of cancer cells. The activities of Rhos are regulated by molecules …

The CCN family members cysteine-rich 61 (Cyr61/CCN1), connective tissue growth factor (CTGF/CCN2)
and nephroblastoma over-expressed (Nov/CCN3) play diverse roles in cells, …

Nipple-sparing mastectomy (NSM) is increasingly popular as a procedure for the treatment
of breast cancer and as a prophylactic procedure for those at high risk of developing the …

BACKGROUND The use of sentinel lymph node biopsy (SLNB) following neoadjuvant
chemotherapy (NAC) in patients presenting with clinically positive lymph nodes remains …

BACKGROUND: Skin-sparing mastectomy represents a new surgical approach that allows a
mastectomy while preserving the natural skin envelope of the breast. It facilitates immediate …

Background Suppressors of cytokine signaling (SOCS) are important negative feedback
regulators of the JAK/STAT signaling pathway, and have been recently investigated for their role …

Lamin A/C (LMNA), lamin B1 (LMNB1) and lamin B receptor (LBR) have key roles in
nuclear structural integrity and chromosomal stability. In this study, we have studied the …

Background SET domain containing protein 2 (SETD2) is a histone methyltransferase that is
involved in transcriptional elongation. There is evidence that SETD2 interacts with p53 and …

There is a growing body of evidence that COX-2 expression sa fundamental step in breast
cancer pathogenesis acting through prostaglandin-dependent and independent mechanisms. …