The objective of this study was to examine the effect of autophagy on stress-induced M2
macrophage polarization in the tumor microenvironment of breast cancer and to determine …

Objective To examine the effect of pSer9-GSK-3β on breast cancer and to determine
whether the underlying metabolic and immunological mechanism is associated with ROS/eIF2B …

PTEN has been studied in several tumor models as a tumor suppressor. In this study, we
explored the role of PTEN in the inhibition state of polarized M2 subtype of macrophage in …

Increasing evidence suggests tumor-associated macrophages (TAMs) are polarized M2
subtype of macrophage that exerts pro-tumor effects and promote the malignancy of some …

Monocarboxylate transporter‐4 ( MCT 4), a monocarboxylic acid transporter, demonstrates
significantly increased expression in the majority of malignancies. We performed an …

Purpose Prior studies have noted that zinc finger E-box binding homeobox 1 (ZEB1) is a
master transcription regulator, affecting the expression of nearly 2000 genes in breast cancer …

Purpose Chronic stress and related hormones are key in cancer progression. Peroxisome
proliferator-activated receptor γ (PPARγ) and its agonists was reported that inducing anti-…

Background Indoleamine-2,3-dioxygenase 1 (IDO1) is an important enzyme for altering the
tumour microenvironment and assisting tumour cells to escape the immune system. Results …

Stress and its related hormones epinephrine (E) and norepinephrine (NE) play a crucial role
in tumor progression. Macrophages in the tumor microenvironment (TME) polarized to M2 is …

The study was designed to investigate the effect of estradiol on the excitatory effect of
oxytocin (OT) on colon motility. Female Wistar rats were used, and some of them were …