Cardiac hypertrophy, characterized by the enlargement of cardiomyocytes, is initially an
adaptive response to physiological and pathological stimuli. Decompensated cardiac …

Background Sonodynamic therapy (SDT) was developed as a localized ultrasound-activated
cytotoxic therapy for cancer. The ability of SDT to destroy target tissues selectively is …

Background: In advanced atherosclerosis, chronic endoplasmic reticulum (ER) stress induces
foam cells apoptosis and generates inflammatory reactions. Methods: THP-1 macrophage-…

Reactive oxygen species (ROS) elevation and mitochondrial membrane potential (MMP)
loss have been proven recently to be involved in sonodynamic therapy (SDT)-induced …

Purpose To investigate the sonoactivity of hypericin (HY), together with its sonodynamic
effect on THP-1 macrophages and the underlying mechanism. Materials and methods CCK-8 …

Background: Protoporphyrin IX (PpIX) and its derivatives are widely used in photodynamic
therapy (PDT) to kill cancer cells. Studies showed that the application of these drugs could …

Background Cancer-associated fibroblasts (CAFs) play important roles in cancer development
and progression. Recent studies show that p53 plays a cell non-autonomous tumor-…

Aging process in mammals is associated with a decline in amplitude and a long period of
circadian behaviors which are regulated by a central circadian regulator in the …

Background Allergic diseases typically refer to a heterogeneous group of conditions
primarily caused by the activation of mast cells or eosinophils, including atopic dermatitis (AD), …

Type I interferons (IFN‐Is) are a class of proinflammatory cytokines produced in response to
viruses and environmental stimulations, resulting in chronic inflammation and even …