The current status of solitary fibrous tumor: diagnostic features, variants, and genetics

K Thway, W Ng, J Noujaim… - … Journal of Surgical …, 2016 - journals.sagepub.com
Solitary fibrous tumor (SFT) is a fibroblastic mesenchymal tumor originally described in the
pleura but now shown at almost every anatomic site. Histopathologically, SFT is …

Dermatofibrosarcoma protuberans: pathology, genetics, and potential therapeutic strategies

K Thway, J Noujaim, RL Jones, C Fisher - Annals of diagnostic pathology, 2016 - Elsevier
Dermatofibrosarcoma protuberans (DFSP), the most common dermal sarcoma, is a
malignant fibroblastic tumor most frequently arising in middle-aged adults. It is typically a low-grade …

Epithelioid sarcoma: diagnostic features and genetics

K Thway, RL Jones, J Noujaim… - Advances in anatomic …, 2016 - journals.lww.com
Epithelioid sarcoma (ES) is a rare, aggressive soft-tissue neoplasm of uncertain differentiation,
characterized by nodular aggregates of epithelioid cells, which are immunoreactive to …

Dedifferentiated liposarcoma: updates on morphology, genetics, and therapeutic strategies

K Thway, RL Jones, J Noujaim, S Zaidi… - Advances in …, 2016 - journals.lww.com
Well-differentiated liposarcoma (WDL) and dedifferentiated liposarcoma (DDL) form the
largest subgroup of liposarcomas, and represent a morphologic and behavioral spectrum of 1 …

[HTML][HTML] The spectrum of EWSR1-rearranged neoplasms at a tertiary sarcoma centre; assessing 772 tumour specimens and the value of current ancillary molecular …

J Noujaim, RL Jones, J Swansbury, D Gonzalez… - British Journal of …, 2017 - nature.com
Background: EWSR1 rearrangements were first identified in Ewing sarcoma, but the
spectrum of EWSR1-rearranged neoplasms now includes many soft tissue tumour subtypes …

[HTML][HTML] Canadian consensus for biomarker testing and treatment of TRK fusion cancer in adults

…, M Hyrcza, M Krzyzanowska, B Melosky, J Noujaim… - Current …, 2021 - mdpi.com
The tyrosine receptor kinase (TRK) inhibitors larotrectinib and entrectinib were recently
approved in Canada for the treatment of solid tumours harbouring neurotrophic tyrosine receptor …

[HTML][HTML] Dermatofibrosarcoma protuberans: from translocation to targeted therapy

J Noujaim, K Thway, C Fisher… - Cancer Biology & …, 2015 - ncbi.nlm.nih.gov
Dermatofibrosarcoma protuberans (DFSP), the most common dermal sarcoma, is a low-grade,
slow growing fibroblastic malignant neoplasm that most frequently affects middle aged …

Adult pleomorphic rhabdomyosarcoma: a multicentre retrospective study

J Noujaim, K Thway, RL Jones, A Miah… - Anticancer …, 2015 - ar.iiarjournals.org
Background: Pleomorphic rhabdomyosarcoma (RMS) is a rare sub-type of RMS. Optimal
treatment remains undefined. Patients and Methods: Between 1995 and 2014, 45 patients …

Desmoplastic small round cell tumor: pathology, genetics, and potential therapeutic strategies

K Thway, J Noujaim, S Zaidi, AB Miah… - … journal of surgical …, 2016 - journals.sagepub.com
Desmoplastic small round cell tumor (DSRCT) is an aggressive small round cell neoplasm
which predominantly occurs intra-abdominally in adolescents and young adults with a male …

[HTML][HTML] Epithelioid sarcoma: opportunities for biology-driven targeted therapy

J Noujaim, K Thway, Z Bajwa, A Bajwa, RG Maki… - Frontiers in …, 2015 - frontiersin.org
Epithelioid sarcoma (ES) is a soft tissue sarcoma of children and young adults for which the
preferred treatment for localized disease is wide surgical resection. Medical management is …