Human induced pluripotent stem (iPS) cells are remarkably similar to embryonic stem (ES)
cells, but recent reports indicate that there may be important differences between them. We …

With an ever-increasing amount of (meta)genomic data being deposited in sequence databases,
(meta)genome mining for natural product biosynthetic pathways occupies a critical role …

Individuals homozygous for the CC chemokine receptor type 5 gene with 32-bp deletions (CCR5Δ32)
are resistant to HIV-1 infection. In this study, we generated induced pluripotent …

It is largely recognized that microRNAs (miRNAs) function to silence gene expression by
targeting 3′UTR regions. However, miRNAs have also been implicated to positively-regulate …

The innovation of reprogramming somatic cells to induced pluripotent stem cells provides a
possible new approach to treat β-thalassemia and other genetic diseases such as sickle cell …

Recent studies have shown that a locus responsible for hereditary nonpolyposis colorectal
cancer (HNPCC) is on chromosome 2p and that tumors developing in these patients contain …

The human naive pluripotent stem cell (PSC) state, corresponding to a pre-implantation stage
of development, has been difficult to capture and sustain in vitro. We report that the Hippo …

Porcine reproductive and respiratory syndrome (PRRS) has been one of the most economically
important diseases affecting swine industry worldwide and causes great economic …

Fluorescent RNAs, aptamers that bind and activate small fluorogenic dyes, have provided a
particularly attractive approach to visualizing RNAs in live cells. However, the simultaneous …

Argonaute proteins are often credited for their cytoplasmic activities in which they function as
central mediators of the RNAi platform and microRNA (miRNA)-mediated processes. They …