The goal of cell culture process intensification is to increase volumetric productivity, generally
by increasing viable cell density (VCD), cell specific productivity or production bioreactor …

Perchlorate (ClO 4 - ) release into the environment has occurred primarily in association
with its manufacture and use in solid rocket propellant. When released into groundwater, …

Fabric-based micro-supercapacitors have a great potential in the field of wearable flexible
energy storage devices because of the controllable volume, changeable structure, intrinsic …

Purpose Tumor growth relies on the sufficient blood supply and continuously requires new
blood vessels to maintain, which lead to vascular abnormalities (Folkman, N Engl J Med 285:…

During biopharmaceutical process development, it is important to improve titer to reduce
drug manufacturing costs and to deliver comparable quality attributes of therapeutic proteins, …

Process analytical technology (PAT) has been defined by the Food and Drug Administration
as a system for designing, analyzing, and controlling manufacturing through timely …

To explore the optimal treatment strategy for patients who harbor sensitive EGFR mutations,
a head‐to‐head study was performed to compare chemotherapy and gefitinib in …

Process intensification has shown great potential to increase productivity and reduce costs in
biomanufacturing. This case study describes the evolution of a manufacturing process from …

Introduction There are a number of uncommon EGFR mutations whose associations with
TKIs are not well clarified. Here, we summarize the clinical data of patients with multiple …

Drug substance (DS) color is an important quality attribute for release, stability and comparability
studies of biologics. With the increase of DS concentrations and biologics pipelines …