Myeloid-derived suppressor cells (MDSCs) are a heterogeneous family of myeloid cells that
suppress T cell immunity in tumor-bearing hosts. In patients with colon cancer, MDSCs have …

Without any sample pretreatment, trace amounts of melamine in various milk products were
rapidly detected noting the characteristic fragments (ie, m/z 110, 85, and 60) in the MS/MS …

Aging-related, nonresolving inflammation in both the central nervous system (CNS) and
periphery predisposes individuals to the development of neurodegenerative disorders (NDDs). …

Emerging evidence suggests that astrocyte loss is one of the most important pathological
features in the hippocampus of patients with major depressive disorder (MDD) and depressive …

The function and regulation of different heterogeneous reactive states of astrocytes in depression
remain unclear. Here, we demonstrate that neurotoxic reactive (A1-like) astrocytes are …

Background: Our previous study demonstrated that metabolic inflammation exacerbates
dopaminergic neuronal degeneration in type 2 diabetes mice. Metformin, a typical oral …

Atomic investigation of point defects is the basis for exploring the mechanisms underlying
the macro performance of materials under irradiation. Owing to the complex local disordered …

We examine the challenges to China's transition to a low carbon electricity system, in which
renewable energy would play a significant role. China's electricity system currently lacks the …

Aquaporin-4 (AQP4), a key molecule for maintaining water and ion homeostasis in the central
nervous system, is expressed in adult neural stem cells (ANSCs) as well as astrocytes. …

Although multiple hypotheses had been proposed to clarify the causes of depression, the
accurate pathogenesis and effective treatment of depression still need to be solved. …