User profiles for Jianghong Rao

Jianghong Rao

Department of Radiology and Chemistry, Stanford University
Verified email at stanford.edu
Cited by 18215

Self-illuminating quantum dot conjugates for in vivo imaging

MK So, C Xu, AM Loening, SS Gambhir, J Rao - Nature biotechnology, 2006 - nature.com
Fluorescent semiconductor quantum dots hold great potential for molecular imaging in vivo
1 , 2 , 3 , 4 , 5 . However, the utility of existing quantum dots for in vivo imaging is limited …

Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivo

…, L Tong, SS Tee, G Tikhomirov, DW Felsher, J Rao - Nature …, 2014 - nature.com
Directed self-assembly of small molecules in living systems could enable a myriad of
applications in biology and medicine, and already this has been used widely to synthesize …

Semiconducting polymer nanoparticles as photoacoustic molecular imaging probes in living mice

…, JV Jokerst, J Mei, SS Gambhir, Z Bao, J Rao - Nature …, 2014 - nature.com
Photoacoustic imaging holds great promise for the visualization of physiology and pathology
at the molecular level with deep tissue penetration and fine spatial resolution. To fully utilize …

A tumor‐specific cascade amplification drug release nanoparticle for overcoming multidrug resistance in cancers

…, J Tang, Y Piao, X Liu, Z Zhou, J Gao, J Rao… - Advanced …, 2017 - Wiley Online Library
A cascade amplification release nanoparticle (CARN) is constructed by the coencapsulation
of β‐lapachone and a reactive‐oxygen‐species (ROS)‐responsive doxorubicin (DOX) …

A Trivalent System from Vancomycin·d-Ala-d-Ala with Higher Affinity Than Avidin·Biotin

J Rao, J Lahiri, L Isaacs, RM Weis, GM Whitesides - Science, 1998 - science.org
Tris(vancomycin carboxamide) binds a trivalent ligand derived fromd-Ala-d-Ala with very
high affinity: dissociation constant (K d ) ≈ 4 × 10 –17 ± 1 × 10 –17 M. High-affinity trivalent …

Nanotechnology strategies to advance outcomes in clinical cancer care

…, MS Bradbury, GM Lanza, AE Nel, J Rao… - ACS …, 2018 - ACS Publications
Ongoing research into the application of nanotechnology for cancer treatment and diagnosis
has demonstrated its advantages within contemporary oncology as well as its intrinsic …

Fluorescence imaging in vivo: recent advances

J Rao, A Dragulescu-Andrasi, H Yao - Current opinion in biotechnology, 2007 - Elsevier
In vivo fluorescence imaging uses a sensitive camera to detect fluorescence emission from
fluorophores in whole-body living small animals. To overcome the photon attenuation in …

Particle size, surface coating, and PEGylation influence the biodistribution of quantum dots in living mice

…, A Aharoni, S Keren, LA Bentolila, J Li, J Rao… - Small, 2009 - Wiley Online Library
This study evaluates the influence of particle size, PEGylation, and surface coating on the
quantitative biodistribution of near‐infrared‐emitting quantum dots (QDs) in mice. Polymer‐ or …

Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing

AJ Shuhendler, K Pu, L Cui, JP Uetrecht, J Rao - Nature biotechnology, 2014 - nature.com
Current drug-safety assays for hepatotoxicity rely on biomarkers with low predictive power.
The production of radical species, specifically reactive oxygen species (ROS) and reactive …

Recent progress on semiconducting polymer nanoparticles for molecular imaging and cancer phototherapy

J Li, J Rao, K Pu - Biomaterials, 2018 - Elsevier
As a new class of organic optical nanomaterials, semiconducting polymer nanoparticles (SPNs)
have the advantages of excellent optical properties, high photostability, facile surface …