MicroRNA Expression Profiling in Human Ovarian Cancer: miR-214 Induces Cell Survival and Cisplatin Resistance by Targeting PTEN
H Yang, W Kong, L He, JJ Zhao, JD O'Donnell, J Wang… - Cancer research, 2008 - AACR
MicroRNAs (miRNA) represent a novel class of genes that function as negative regulators of
gene expression. Recently, miRNAs have been implicated in several cancers. However, …
gene expression. Recently, miRNAs have been implicated in several cancers. However, …
MicroRNA-155 is regulated by the transforming growth factor β/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA
W Kong, H Yang, L He, J Zhao, D Coppola… - … and cellular biology, 2008 - Taylor & Francis
Transforming growth factor β (TGF-β) signaling facilitates metastasis in advanced malignancy.
While a number of protein-encoding genes are known to be involved in this process, …
While a number of protein-encoding genes are known to be involved in this process, …
[HTML][HTML] MicroRNA-221/222 negatively regulates estrogen receptorα and is associated with tamoxifen resistance in breast cancer
JJ Zhao, J Lin, H Yang, W Kong, L He, X Ma… - Journal of Biological …, 2008 - ASBMB
A search for regulators of estrogen receptor α (ERα) expression has yielded a set of microRNAs
(miRNAs) for which expression is specifically elevated in ERα-negative breast cancer. …
(miRNAs) for which expression is specifically elevated in ERα-negative breast cancer. …
microRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma
JJ Zhao, J Lin, T Lwin, H Yang, J Guo… - Blood, The Journal …, 2010 - ashpublications.org
Mantle cell lymphoma (MCL) is one of the most aggressive B-cell lymphomas. Although
several protein-coding genes are altered, expression signature and importance of microRNA (…
several protein-coding genes are altered, expression signature and importance of microRNA (…
Identification of miRNAs associated with tumorigenesis of retinoblastoma by miRNA microarray analysis
JJ Zhao, J Yang, J Lin, N Yao, Y Zhu, J Zheng… - Child's Nervous …, 2009 - Springer
Introduction MicroRNAs (miRNAs) are small (∽22 nucleotides) regulatory RNAs which play
fundamental roles in many human diseases, including cancer. There is no report on the …
fundamental roles in many human diseases, including cancer. There is no report on the …
Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signaling
…, D Zhu, GH Bird, K Sukhdeo, JJ Zhao… - Science translational …, 2012 - science.org
Deregulated Wnt/β-catenin signaling underlies the pathogenesis of a broad range of human
cancers, yet the development of targeted therapies to disrupt the resulting aberrant …
cancers, yet the development of targeted therapies to disrupt the resulting aberrant …
miR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/β-catenin/BCL9 pathway
Wnt/β-catenin signaling underlies the pathogenesis of a broad range of human cancers,
including the deadly plasma cell cancer multiple myeloma. In this study, we report that …
including the deadly plasma cell cancer multiple myeloma. In this study, we report that …
Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma
…, G Yang, Y Calle, Y Hu, J Lin, JJ Zhao… - Blood, The Journal …, 2012 - ashpublications.org
Bruton tyrosine kinase (Btk) has a well-defined role in B-cell development, whereas its
expression in osteoclasts (OCs) further suggests a role in osteoclastogenesis. Here we …
expression in osteoclasts (OCs) further suggests a role in osteoclastogenesis. Here we …
Phylogenetic analysis of the haemagglutinin gene of canine distemper virus strains detected from breeding foxes, raccoon dogs and minks in China
JJ Zhao, XJ Yan, XL Chai, V Martella, GL Luo… - Veterinary …, 2010 - Elsevier
Canine distemper virus (CDV) infects a variety of carnivores, including wild and domestic
Canidae. Genetic/antigenic heterogeneity has been observed among the various CDV strains, …
Canidae. Genetic/antigenic heterogeneity has been observed among the various CDV strains, …
Targeting the MALAT1/PARP1/LIG3 complex induces DNA damage and apoptosis in multiple myeloma
…, Z Gong, F Reu, J Maciejewski, Q Yi, JJ Zhao - Leukemia, 2018 - nature.com
Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a highly conserved long
non-coding RNA (lncRNA). Overexpression of MALAT1 has been demonstrated to related …
non-coding RNA (lncRNA). Overexpression of MALAT1 has been demonstrated to related …