Faecal microbiota transplantation protects against radiation‐induced toxicity

…, L Zhou, S Zhao, D Luo, Q Zheng, J Dong… - EMBO molecular …, 2017 - embopress.org
Severe radiation exposure may cause acute radiation syndrome, a possibly fatal condition
requiring effective therapy. Gut microbiota can be manipulated to fight against many diseases. …

Activation of STAT3 and Bcl-2 and reduction of reactive oxygen species (ROS) promote radioresistance in breast cancer and overcome of radioresistance with …

L Lu, J Dong, L Wang, Q Xia, D Zhang, H Kim, T Yin… - Oncogene, 2018 - nature.com
Radiotherapy significantly improves the therapeutic outcomes and survival of breast cancer
patients. However, the acquired resistance to this therapeutic modality is a major clinical …

Gut commensal derived-valeric acid protects against radiation injuries

Y Li, J Dong, H Xiao, S Zhang, B Wang, M Cui… - Gut microbes, 2020 - Taylor & Francis
Background Hematopoietic and intestinal systems side effects are frequently found in patients
who suffered from accidental or medical radiation exposure. In this case, we investigated …

[PDF][PDF] Oral microbiota affects the efficacy and prognosis of radiotherapy for colorectal cancer in mouse models

J Dong, Y Li, H Xiao, S Zhang, B Wang, H Wang, Y Li… - Cell reports, 2021 - cell.com
Radiotherapy is inevitably intertwined with various side effects impairing the quality of life of
cancer patients. Here, we report the possibility that alterations of the oral microbiota …

LncRNA HOTAIR enhances breast cancer radioresistance through facilitating HSPA1A expression via sequestering miR‐449b‐5p

S Zhang, B Wang, H Xiao, J Dong, Y Li, C Zhu… - Thoracic …, 2020 - Wiley Online Library
Background Breast cancer (BRCA) is the leading cause of cancer‐related death in women
worldwide. Pre‐ and postoperative radiotherapy play a pivotal role in BRCA treatment but its …

Comparison of plasma electrolytic oxidation of zirconium alloy in silicate-and aluminate-based electrolytes and wear properties of the resulting coatings

Y Cheng, F Wu, J Dong, X Wu, Z Xue, E Matykina… - Electrochimica …, 2012 - Elsevier
Plasma electrolytic oxidation of Zircaloy-2 at constant rms current is examined in silicate and
aluminate electrolytes, revealing significantly different behaviors in the growth kinetics and …

[HTML][HTML] Circadian rhythm shapes the gut microbiota affecting host radiosensitivity

…, S Zhao, Q Zheng, Y Li, Y Zhao, J Dong… - International journal of …, 2016 - mdpi.com
Modern lifestyles, such as shift work, nocturnal social activities, and jet lag, disturb the
circadian rhythm. The interaction between mammals and the co-evolved intestinal microbiota …

[HTML][HTML] Stable colonization of Akkermansia muciniphila educates host intestinal microecology and immunity to battle against inflammatory intestinal diseases

B Wang, X Chen, Z Chen, H Xiao, J Dong, Y Li… - … & Molecular Medicine, 2023 - nature.com
Gut microbial preparations are widely used in treating intestinal diseases but show mixed
success. In this study, we found that the therapeutic efficacy of A. muciniphila for dextran …

Sexual dimorphism of gut microbiota dictates therapeutics efficacy of radiation injuries

M Cui, H Xiao, Y Li, S Zhang, J Dong… - Advanced …, 2019 - Wiley Online Library
Accidental or iatrogenic ionizing radiation exposure precipitates acute and chronic radiation
injuries. The traditional paradigm of mitigating radiotherapy‐associated adverse side effects …

B7-H3 regulates lipid metabolism of lung cancer through SREBP1-mediated expression of FASN

D Luo, H Xiao, J Dong, Y Li, G Feng, M Cui… - … and biophysical research …, 2017 - Elsevier
B7-H3 is a glycoprotein overexpressed in cancer, but its functional contribution in this setting
remains poorly understood. In the present study, we identified that the overexpression of B7-…