Cancer stem cells (CSCs), a unique subset of undifferentiated cells with stem cell-like properties,
have emerged as driving forces in mediating tumor growth, metastasis, and therapeutic …

INTRODUCTION Cancer immunotherapies that target tumor-specific T cells have benefited
many cancer patients, but the clinical efficacy varies greatly among different cancer types. …

Background D2 gastrectomy is recommended in US and European guidelines, and is
preferred in east Asia, for patients with resectable gastric cancer. Adjuvant chemotherapy …

Tumor-infiltrating myeloid cells (TIMs) are key regulators in tumor progression, but the
similarity and distinction of their fundamental properties across different tumors remain elusive. …

Hepatocellular carcinoma (HCC) is a leading cause of death worldwide. Using cDNA
microarrays to characterize patterns of gene expression in HCC, we found consistent differences …

Background The CLASSIC trial was done to compare adjuvant capecitabine plus oxaliplatin
versus observation after D2 gastrectomy for patients with stage II or III gastric cancer. The …

Objective The intra-operative air leak test (ALT) is a common intraoperative test used to
identify mechanically insufficient anastomosis. This meta-analysis aims to determine whether …

Importance Laparoscopic distal gastrectomy is accepted as a more effective approach to
conventional open distal gastrectomy for early-stage gastric cancer. However, efficacy for …

Surgery is essential for global cancer care in all resource settings. Of the 15·2 million new
cases of cancer in 2015, over 80% of cases will need surgery, some several times. By 2030, …

Background The optimal perioperative chemotherapeutic regimen for locally advanced
gastric cancer remains undefined. We evaluated the efficacy and safety of perioperative and …