Safety and immunogenicity from a phase I trial of inactivated severe acute respiratory syndrome coronavirus vaccine

…, X Chen, YX Liu, H Gao, YP Jia, Y Liu… - Antiviral …, 2007 - journals.sagepub.com
Background Emergence of severe acute respiratory syndrome (SARS) from the winter of
2002 to the spring of 2003 has caused a serious threat to public health. Methods To evaluate …

CXCR4-targeted lipid-coated PLGA nanoparticles deliver sorafenib and overcome acquired drug resistance in liver cancer

…, YC Sung, YC Liu, WH Chiang, CC Chang, JY Liu… - Biomaterials, 2015 - Elsevier
Sorafenib, a multikinase inhibitor, has been used as an anti-angiogenic agent against highly
vascular hepatocellular carcinoma (HCC) – yet associated with only moderate therapeutic …

Development and characterization of sorafenib-loaded PLGA nanoparticles for the systemic treatment of liver fibrosis

TT Lin, DY Gao, YC Liu, YC Sung, D Wan, JY Liu… - Journal of controlled …, 2016 - Elsevier
Sorafenib is a tyrosine kinase inhibitor that has recently been shown to be a potential
antifibrotic agent. However, a narrow therapeutic window limits the clinical use and therapeutic …

The stress granule protein G3BP1 promotes pre‐condensation of cGAS to allow rapid responses to DNA

M Zhao, T Xia, JQ Xing, LH Yin, XW Li, J Pan, JY Liu… - EMBO …, 2022 - embopress.org
Cyclic GMP‐AMP synthase (cGAS) functions as a key sensor for microbial invasion and
cellular damage by detecting emerging cytosolic DNA. Here, we report that GTPase‐activating …

Separation of vegetable oil compounds and solvent recovery using commercial organic solvent nanofiltration membranes

GM Shi, MHDA Farahani, JY Liu, TS Chung - Journal of membrane science, 2019 - Elsevier
Solvent recovery and separation of oil compounds by means of thermal evaporation processes
consume a huge amount of energy. Organic solvent nanofiltration (OSN) is an energy-…

Delivery of siRNA using CXCR4-targeted nanoparticles modulates tumor microenvironment and achieves a potent antitumor response in liver cancer

JY Liu, T Chiang, CH Liu, GG Chern, TT Lin, DY Gao… - Molecular Therapy, 2015 - cell.com
Antiangiogenic therapy has recently emerged as a highly promising therapeutic strategy for
treating hepatocellular carcinoma (HCC). However, the only clinically approved systemic …

[HTML][HTML] Advances in circulating microRNAs as diagnostic and prognostic markers for ovarian cancer

H Zheng, JY Liu, FJ Song, KX Chen - Cancer biology & medicine, 2013 - ncbi.nlm.nih.gov
Ovarian cancer is one of the most lethal malignant gynecological tumors. More than 70% of
patients with ovarian cancer are diagnosed at advanced stage. The 5-year survival in …

Gadolinium phosphate/chitosan scaffolds promote new bone regeneration via Smad/Runx2 pathway

PP Zhao, HR Hu, JY Liu, QF Ke, XY Peng… - Chemical Engineering …, 2019 - Elsevier
Gadolinium (Gd) is one of trace rare earth elements (REEs) existing in human bones;
however, the underlying mechanisms of Gd element on positive cell response and bone …

Fabrication of alginate based microgels for drug-sustained release: In-vitro and in-vivo evaluation

M Suhail, XR Li, JY Liu, WC Hsieh, YW Lin… - International Journal of …, 2021 - Elsevier
The current study was conducted to evaluate and analyze the effect of alginate, itaconic acid,
and N,N′-methylene bisacrylamide in formulation of a novel alginate based microgels for …

Synthesis of glutamic acid/polyvinyl alcohol based hydrogels for controlled drug release: In-vitro characterization and in-vivo evaluation

M Suhail, CM Shih, JY Liu, WC Hsieh, YW Lin… - Journal of Drug Delivery …, 2022 - Elsevier
The aim of the current study was to prepare glutamic acid/polyvinyl alcohol based hydrogels
by the free radical polymerization technique. The FTIR analysis of glutamic acid, polyvinyl …