[HTML][HTML] Epidemiology of ovarian cancer: a review

BM Reid, JB Permuth, TA Sellers - Cancer biology & medicine, 2017 - ncbi.nlm.nih.gov
Ovarian cancer (OC) is the seventh most commonly diagnosed cancer among women in the
world and the tenth most common in China. Epithelial OC is the most predominant …

Genome-wide meta-analyses of breast, ovarian, and prostate cancer association studies identify multiple new susceptibility loci shared by at least two cancer types

…, JL Stanford, J Benítez, JA Doherty, JB Permuth… - Cancer discovery, 2016 - AACR
Breast, ovarian, and prostate cancers are hormone-related and may have a shared genetic
basis, but this has not been investigated systematically by genome-wide association (GWA) …

[HTML][HTML] Prospective, multi-institutional, real-time next-generation sequencing of pancreatic cyst fluid reveals diverse genomic alterations that improve the clinical …

…, RH Hruban, PD Bell, K Smith, JB Permuth… - Gastroenterology, 2023 - Elsevier
Background & Aims Next-generation sequencing (NGS) of pancreatic cyst fluid is a useful
adjunct in the assessment of patients with pancreatic cyst. However, previous studies have …

[HTML][HTML] Combining radiomic features with a miRNA classifier may improve prediction of malignant pathology for pancreatic intraductal papillary mucinous neoplasms

JB Permuth, J Choi, Y Balarunathan, J Kim, DT Chen… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Intraductal papillary mucinous neoplasms (IPMNs) are pancreatic cancer precursors incidentally
discovered by cross-sectional imaging. Consensus guidelines for IPMN management …

Cross-cancer genome-wide analysis of lung, ovary, breast, prostate, and colorectal cancer reveals novel pleiotropic associations

…, F Wiklund, WC Willett, EL Goode, JB Permuth… - Cancer research, 2016 - AACR
Identifying genetic variants with pleiotropic associations can uncover common pathways
influencing multiple cancers. We took a two-stage approach to conduct genome-wide …

[HTML][HTML] Linc-ing circulating long non-coding RNAs to the diagnosis and malignant prediction of intraductal papillary mucinous neoplasms of the pancreas

JB Permuth, DT Chen, SJ Yoder, J Li, AT Smith… - Scientific reports, 2017 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease that lacks effective
biomarkers for early detection. We hypothesized that circulating long non-coding RNAs (…

[HTML][HTML] Rare germline variants in ATM predispose to prostate cancer: a PRACTICAL Consortium Study

…, C Huff, D Li, Y Yao, P Scheet, JB Permuth… - European Urology …, 2021 - Elsevier
Background Germline ATM mutations are suggested to contribute to predisposition to prostate
cancer (PrCa). Previous studies have had inadequate power to estimate variant effect …

Establishing a living biobank of patient-derived organoids of intraductal papillary mucinous neoplasms of the pancreas

…, B Sarcar, JK Teer, GM DeNicola, JB Permuth… - Laboratory …, 2021 - nature.com
Pancreatic cancer (PaCa) is the third leading cause of cancer-related deaths in the United
States. There is an unmet need to develop strategies to detect PaCa at an early, operable …

Neoadjuvant chemotherapy for intrahepatic cholangiocarcinoma: a propensity score survival analysis supporting use in patients with high-risk disease

O Utuama, JB Permuth, G Dagne… - Annals of Surgical …, 2021 - Springer
Background Upfront surgery is the current standard for resectable intrahepatic cholangiocarcinoma
(ICC) despite high treatment failure with this approach. We sought to examine the …

Quantifying the genetic correlation between multiple cancer types

…, K Rand, SB Gruber, D Conti, JB Permuth… - … Biomarkers & Prevention, 2017 - AACR
Background: Many cancers share specific genetic risk factors, including both rare high-penetrance
mutations and common SNPs identified through genome-wide association studies (…