An aryl hydrocarbon receptor-mediated amplification loop that enforces cell migration in ER−/PR−/Her2− human breast cancer cells
…, A Ramirez-Cardenas, E Landesman, I Laklouk… - Molecular …, 2016 - ASPET
The endogenous ligand-activated aryl hydrocarbon receptor (AHR) plays an important role
in numerous biologic processes. As the known number of AHR-mediated processes grows, …
in numerous biologic processes. As the known number of AHR-mediated processes grows, …
[HTML][HTML] Understanding the tumor immune microenvironment in renal cell carcinoma
DD Shapiro, B Dolan, IA Laklouk, S Rassi, T Lozar… - Cancers, 2023 - mdpi.com
Simple Summary Over the last decade there has been a significant increase in the number
of therapies that activate the host’s immune system to target and eliminate renal cell …
of therapies that activate the host’s immune system to target and eliminate renal cell …
[HTML][HTML] Biological data annotation via a human-augmenting AI-based labeling system
D van der Wal, I Jhun, I Laklouk, J Nirschl… - NPJ digital …, 2021 - nature.com
Biology has become a prime area for the deployment of deep learning and artificial intelligence
(AI), enabled largely by the massive data sets that the field can generate. Key to most AI …
(AI), enabled largely by the massive data sets that the field can generate. Key to most AI …
Oncocytic intraductal carcinoma of salivary glands: a distinct variant with TRIM33–RET fusions and BRAF V600E mutations
…, RD Whaley, K Ogura, H Imai, I Laklouk… - …, 2021 - Wiley Online Library
Aims Salivary gland intraductal carcinoma (IDC) is a complex ductal neoplasm surrounded
by a layer of myoepithelial cells. Recent insights have shown that there are three different …
by a layer of myoepithelial cells. Recent insights have shown that there are three different …
[HTML][HTML] Non-metastatic clear cell renal cell carcinoma immune cell infiltration heterogeneity and prognostic ability in patients following surgery
DD Shapiro, T Lozar, L Cheng, E Xie, I Laklouk… - Cancers, 2024 - mdpi.com
Simple Summary It is difficult to predict which patients with non-metastatic clear cell renal
cell carcinoma (ccRCC) will develop metastatic disease after nephrectomy. Recent studies …
cell carcinoma (ccRCC) will develop metastatic disease after nephrectomy. Recent studies …
[HTML][HTML] Stress Keratin 17 Is a Predictive Biomarker Inversely Associated with Response to Immune Check-Point Blockade in Head and Neck Squamous Cell …
T Lozar, I Laklouk, AE Golfinos, N Gavrielatou, J Xu… - Cancers, 2023 - mdpi.com
Simple Summary Between 15 and 35% of head and neck cancer patients respond to
immune check-point blockade therapy (ICB), and some may experience potentially life-threatening …
immune check-point blockade therapy (ICB), and some may experience potentially life-threatening …
Intraductal carcinoma of the salivary gland with NCOA4-RET: expanding the morphologic spectrum and an algorithmic diagnostic approach
AS Fisch, I Laklouk, M Nakaguro, V Nosé, LJ Wirth… - Human pathology, 2021 - Elsevier
After the publication of the 2017 World Health Organization Classification of Head and Neck
Tumours, there has been increasing interest in the classification of newly categorized …
Tumours, there has been increasing interest in the classification of newly categorized …
[HTML][HTML] Primary unresectable locally invasive biatrial paraganglioma presenting with chest pain
I Laklouk, ML Soliman, RW Pistey, SR Cerda - Human Pathology: Case …, 2018 - Elsevier
Paragangliomas, neuroendocrine tumors of neural crest origin, commonly occur in the adrenal
medulla where they are called pheochromocytoma. Primary cardiac paragangliomas are …
medulla where they are called pheochromocytoma. Primary cardiac paragangliomas are …
Biological data annotation via a human-augmenting AI-based labeling interface
Biology has become a prime area for the deployment of deep learning and artificial intelligence
(AI), enabled largely by the massive datasets that the field can generate. Key to most AI …
(AI), enabled largely by the massive datasets that the field can generate. Key to most AI …
Penile Blood Gas Sample to Assess Recurrent Priapism
I Laklouk, Y Kataria - Clinical Chemistry, 2019 - academic.oup.com
CASE SUMMARY A technologist questioned an undetectable glucose concentration in an
arterial blood gas sample. Investigation revealed that it was a penile sample collected from a …
arterial blood gas sample. Investigation revealed that it was a penile sample collected from a …