A p38 MAPK inhibitor, FR-167653, ameliorates murine bleomycin-induced pulmonary fibrosis

…, H Morishita, H Fujiwara, I Tachibana… - … of Physiology-Lung …, 2002 - journals.physiology.org
To elucidate the pathophysiology of pulmonary fibrosis, we investigated the involvement of
p38 mitogen-activated protein kinase (MAPK), which is one of the major signal transduction …

Gene therapy for carcinoembryonic antigen-producing human lung cancer cells by cell type-specific expression of herpes simplex virus thymidine kinase gene

T Osaki, Y Tanio, I Tachibana, S Hosoe, T Kumagai… - Cancer research, 1994 - AACR
A carcinoembryonic antigen (CEA)-producing human lung cancer cell line (A549), a nonproducing
human lung cancer cell line (CADO-LC9), and a human uterine cervical cancer (HeLa…

Tetraspanins CD9 and CD81 function to prevent the fusion of mononuclear phagocytes

Y Takeda, I Tachibana, K Miyado… - The Journal of cell …, 2003 - rupress.org
Tetraspanins CD9 and CD81 facilitate the fusion between gametes, myoblasts, or virus-infected
cells. Here, we investigated the role of these tetraspanins in the fusion of mononuclear …

Proteomics‐based identification of α‐enolase as a tumor antigen in non‐small lung cancer

…, H Shiono, M Okumura, T Nishida, I Tachibana… - Cancer …, 2007 - Wiley Online Library
Autoantibodies against tumor antigens represent one type of biomarker that may be assayed
in serum for detection of cancer and monitoring of disease progression. In the present study…

[PDF][PDF] Transcriptomics identify CD9 as a marker of murine IL-10-competent regulatory B cells

…, J Wang, E Pefanis, J Chao, G Rothschild, I Tachibana… - Cell reports, 2015 - cell.com
Regulatory B cells (Breg) have immune suppressive functions in various autoimmune/inflammation
models and diseases and are found to be enriched in diverse B cell subsets. The …

Early [18F]Fluorodeoxyglucose Positron Emission Tomography at Two Days of Gefitinib Treatment Predicts Clinical Outcome in Patients with Adenocarcinoma of the …

R Takahashi, H Hirata, I Tachibana… - Clinical Cancer …, 2012 - AACR
Purpose: Positron emission tomography (PET) with [ 18 F]fluorodeoxyglucose (FDG) is
increasingly used in early assessment of tumor response after chemotherapy. We investigated …

Suppressor of cytokine signalling‐1 gene silencing in acute myeloid leukaemia and human haematopoietic cell lines

…, Y Saito, H Nagai, I Tachibana… - British journal of …, 2004 - Wiley Online Library
The aim of this study was to investigate whether the suppressor of cytokine signalling (SOCS)‐1
can act as a tumour suppressor when functioning as a negative regulator of the Janus …

In silico evaluation of particle transport and deposition in the airways of individual patients with chronic obstructive pulmonary disease

…, M Maeda, D Maki, Y Kinehara, I Tachibana… - European Journal of …, 2022 - Elsevier
Inhalation therapy can effectively treat chronic obstructive pulmonary disease (COPD), but
the physical factors determining the appropriate aerosol delivery into the targeted airways …

Cell surface tetraspanin CD9 mediates chemoresistance in small cell lung cancer

…, H Kida, S Goya, M Yoshida, T Kumagai, I Tachibana… - Cancer research, 2010 - AACR
Small cell lung cancer (SCLC) is an aggressive malignancy with extremely high mortality
due to the appearance of widespread metastases early in its clinical course and rapid …

Role of transmembrane 4 superfamily (TM4SF) proteins CD9 and CD81 in muscle cell fusion and myotube maintenance

I Tachibana, ME Hemler - The Journal of cell biology, 1999 - rupress.org
The role of transmembrane 4 superfamily (TM4SF) proteins during muscle cell fusion has
not been investigated previously. Here we show that the appearance of TM4SF protein, CD9, …