In alternative expression analysis by sequencing (ALEXA-seq), we developed a method to
analyze massively parallel RNA sequence data to catalog transcripts and assess differential …

To define specific pathways important in the multistep transformation process of normal
plasma cells (PCs) to monoclonal gammopathy of uncertain significance (MGUS) and multiple …

The ability to effectively target a tumor to achieve complete regression and cure is the
ultimate goal that drives our need to better understand tumor biology. Recently, SPARC has …

Purpose: Elucidation of candidate colorectal cancer biomarkers often begins by comparing
the expression profiles of cancerous and normal tissue by performing gene expression …

Overcoming resistance to chemotherapy and radiation therapy has been a difficult but
important goal in the effort to cure cancer. We used gene-expression microarrays to identify …

Prolonged survival of pancreatic islet allografts implanted in diabetic BB rats was achieved
by encapsulation of individual islets in a protective biocompatible alginate-polylysine-…

Several factors have been shown to promote the growth of colorectal cancers. Here, we
provide evidence that periostin, a protein with structural and sequence homology with a TGF-β-…

Prostate cancer (PCa) is the most frequently diagnosed cancer in men. Current research on
tumour-related extracellular vesicles (EVs) suggests that exosomes play a significant role in …

… , RKO cells resistant to irinotecan Address all correspondence to: Isabella T. Tai, MD, PhD,
Division of … IT Tai is an MSFHR scholar and a CIHR new investigator. 2This article refers to …

Therapy-refractory disease is one of the main contributors of treatment failure in cancer. In
colorectal cancer (CRC), SPARC can function as a sensitizer to conventional chemotherapy …