Background Whether extended lymphadenectomy for right colon cancer leads to increased
perioperative complications or improves survival is still controversial. This trial aimed to …

Purpose: We investigated the value of circulating tumor DNA (ctDNA) in predicting tumor
response to neoadjuvant chemoradiotherapy (nCRT), monitoring tumor burden, and …

Background Recently, the distinction between left- and right-sided colon cancer (LCC and
RCC) has been brought into focus. RCC is associated with an inferior overall survival and …

Importance The efficacy of laparoscopic vs open surgery for patients with low rectal cancer
has not been established. Objective To compare the short-term efficacy of laparoscopic …

Background Transanal endoscopic microsurgery (TEM) for the treatment of early-stage
rectal cancer has attracted attention due to its advantages of reduced surgical trauma, fewer …

Background Intracorporeal anastomosis (IA) is associated with reduced surgical site
infection (SSI) and other postoperative complications in laparoscopic right colectomy (LRC). …

Background The extent of lymphadenectomy during laparoscopic right colectomy can affect
the oncological outcome and the safety of surgery. The principle of complete mesocolic …

Aim Our aim was to compare short‐ and long‐term oncological outcomes between
laparoscopic and open colectomy in T4 colon cancer. Methods We retrospectively analysed …

Polypyrimidine tract-binding protein 1 (PTBP1) involving in almost all steps of mRNA
regulation including alternative splicing metabolism during tumorigenesis due to its RNA-binding …

BACKGROUND: Patients with locally advanced rectal cancer could be managed by a watch-and-wait
approach if they achieve clinical complete response after preoperative …