DNA damage response–a double-edged sword in cancer prevention and cancer therapy
Genomic stability depends on an efficient DNA damage repair system to keep the chromosomes
intact. Unrepaired DNA damage not only causes cell cycle arrest, apoptosis, but also …
intact. Unrepaired DNA damage not only causes cell cycle arrest, apoptosis, but also …
Potent anti‐leukemia activities of humanized CD19‐targeted Chimeric antigen receptor T (CAR‐T) cells in patients with relapsed/refractory acute lymphoblastic …
…, K Qi, W Sang, LI Zhenyu, M Shi, H Li… - American journal of …, 2018 - Wiley Online Library
Chimeric antigen receptor T (CAR‐T) cell therapy has shown promising results for relapsed/refractory
(R/R) acute lymphoblastic leukemia (ALL). The immune response induced by …
(R/R) acute lymphoblastic leukemia (ALL). The immune response induced by …
Long-term follow-up of combination of B-cell maturation antigen and CD19 chimeric antigen receptor T cells in multiple myeloma
PURPOSE A combination of anti–B-cell maturation antigen (BCMA) and anti-CD19 chimeric
antigen receptor (CAR) T cells induced high response rates in patients with relapsed or …
antigen receptor (CAR) T cells induced high response rates in patients with relapsed or …
Empirical evaluation of smart contract testing: What is the best choice?
Security of smart contracts has attracted increasing attention in recent years. Many
researchers have devoted themselves to devising testing tools for vulnerability detection. Each …
researchers have devoted themselves to devising testing tools for vulnerability detection. Each …
[HTML][HTML] Targeting brain lesions of non-small cell lung cancer by enhancing CCL2-mediated CAR-T cell migration
H Li, EB Harrison, H Li, K Hirabayashi, J Chen… - Nature …, 2022 - nature.com
Metastatic non-small cell lung cancer (NSCLC) remains largely incurable and the prognosis
is extremely poor once it spreads to the brain. In particular, in patients with brain metastases…
is extremely poor once it spreads to the brain. In particular, in patients with brain metastases…
[HTML][HTML] Combination therapy with EpCAM-CAR-NK-92 cells and regorafenib against human colorectal cancer models
…, J Ding, H Liu, H Li, H Li, M Lu, Y Miao, L Li… - Journal of immunology …, 2018 - hindawi.com
Adoptive chimeric antigen receptor-modified T or NK cells (CAR-T or CAR-NK) offer new
options for cancer treatment. CAR-T therapy has achieved encouraging breakthroughs in the …
options for cancer treatment. CAR-T therapy has achieved encouraging breakthroughs in the …
Keap1: one stone kills three birds Nrf2, IKKβ and Bcl-2/Bcl-xL
H Tian, BF Zhang, JH Di, G Jiang, FF Chen, HZ Li, LT Li… - Cancer letters, 2012 - Elsevier
Oxidative stress, implicated in the etiology of cancer, results from an imbalance in the production
of Reactive Oxygen Species (ROS) and cell’s own antioxidant defenses. As a oxidative …
of Reactive Oxygen Species (ROS) and cell’s own antioxidant defenses. As a oxidative …
Anionic nanoplastic contaminants promote Parkinson's disease–associated α-synuclein aggregation
…, AM Duda, E Xu, C Stanhope, A Fu, S Strader, H Li… - Science …, 2023 - science.org
Recent studies have identified increasing levels of nanoplastic pollution in the environment.
Here, we find that anionic nanoplastic contaminants potently precipitate the formation and …
Here, we find that anionic nanoplastic contaminants potently precipitate the formation and …
Evmfuzzer: detect evm vulnerabilities via fuzz testing
Ethereum Virtual Machine (EVM) is the run-time environment for smart contracts and its
vulnerabilities may lead to serious problems to the Ethereum ecology. With lots of techniques …
vulnerabilities may lead to serious problems to the Ethereum ecology. With lots of techniques …
Immunoreceptor TIGIT inhibits the cytotoxicity of human cytokine-induced killer cells by interacting with CD155
B Zhang, W Zhao, H Li, Y Chen, H Tian, L Li… - Cancer Immunology …, 2016 - Springer
T cell Ig and ITIM domain (TIGIT) is a newly identified inhibitory receptor expressed on T
and natural killer (NK) cells. Cytokine-induced killer (CIK) cells express CD3 and CD56 …
and natural killer (NK) cells. Cytokine-induced killer (CIK) cells express CD3 and CD56 …