Studies examining the mechanisms by which the liver incurs injury and then regenerates
usually focus on factors and pathways directly within the liver, neglecting the signaling derived …

This study aims to uncover how specific bacteria and bile acids (BAs) contribute to steatosis
induced by diet and farnesoid X receptor (FXR) deficiency in both genders. A control diet (CD…

Dysregulated bile acid (BA) synthesis or reduced farnesoid X receptor (FXR) levels are found
in patients having metabolic diseases, autoimmune hepatitis, and liver cirrhosis or cancer. …

Dysregulated bile acid (BA) synthesis is accompanied by dysbiosis, leading to compromised
metabolism. This study analyzes the effect of epigallocatechin-3-gallate (EGCG) on diet-…

Background & Aims The pathways regulating liver regeneration have been extensively
studied within the liver. However, the signaling contribution derived from the gut microbiota to …

Background Non-alcoholic fatty liver disease (NAFLD) represents a severe public health
problem. Dysbiosis of gut microbiome has been identified as one of the key environmental …

Patients who have liver cirrhosis and liver cancer also have reduced farnesoid X receptor (FXR).
The current study analyzes the effect of diet through microbiota that affect hepatic …

Because of the significant tumor-suppressive role of microRNA-22 (miR-22), the current
study was designed to understand the regulation of miR-22 and to identify additional …

Branched-chain amino acids (BCAAs), composed of leucine, isoleucine and valine, are
important essential amino acids in human physiology. Decades of studies have revealed their …

Background and aim Hepatitis C virus infection can lead to an enormous health burden
worldwide. Investigating the changes in HCV-related burden between different countries could …