[HTML][HTML] Chronic intermittent hypoxia participates in the pathogenesis of atherosclerosis and perturbs the formation of intestinal microbiota

C Hu, P Wang, Y Yang, J Li, X Jiao, H Yu… - Frontiers in cellular …, 2021 - frontiersin.org
Chronic intermittent hypoxia (CIH) is the prominent signature of highly prevalent obstructive
sleep apnea (OSA) pathophysiology, which leads to increased risk and aggravation of …

[HTML][HTML] Angiopoietin-like protein 8 accelerates atherosclerosis in ApoE−/− mice

X Jiao, Y Yang, L Li, H Yu, Y Yang, J Li, Y Du, J Zhang… - Atherosclerosis, 2020 - Elsevier
Background and aims Angiopoietin-like protein 8 (ANGPTL8) is a hormone involved in
regulating lipid metabolism. Patients with coronary artery disease have markedly higher plasma …

[HTML][HTML] Salidroside Ameliorated Intermittent Hypoxia-Aggravated Endothelial Barrier Disruption and Atherosclerosis via the cAMP/PKA/RhoA Signaling Pathway

L Li, Y Yang, H Zhang, Y Du, X Jiao, H Yu… - Frontiers in …, 2021 - frontiersin.org
Background: Endothelial barrier dysfunction plays a key role in atherosclerosis progression.
The primary pathology of obstructive sleep apnea-hypopnea syndrome is chronic …

[HTML][HTML] Increased circulating angiopoietin-like protein 8 levels are associated with thoracic aortic dissection and higher inflammatory conditions

…, X Jiao, L Li, C Hu, X Zhang, L Pan, H Yu… - … drugs and therapy, 2020 - Springer
Purpose Thoracic aortic dissection (TAD) is characterized by an inflammatory response.
Angiopoietin-like protein 8 (ANGPTL8) is a hormone involved in the regulation of lipid …

Vascular smooth muscle cells specific deletion of angiopoietin-like protein 8 prevents angiotensin II-promoted hypertension and cardiovascular hypertrophy

X Jiao, H Yu, Z Du, L Li, C Hu, Y Du… - Cardiovascular …, 2023 - academic.oup.com
Aims Angiopoietin-like protein 8 (ANGPTL8) plays important roles in lipid metabolism,
glucose metabolism, inflammation, and cell proliferation and migration. Clinical studies have …

[HTML][HTML] Angiopoietin-like protein 8 deficiency attenuates thoracic aortic aneurysm/dissection development in β-aminopropionitrile monofumarate-induced model mice

Y Yang, X Jiao, H Yu, L Li, J Li, X Zhang… - Biochimica et Biophysica …, 2023 - Elsevier
Thoracic aortic aneurysm/dissection (TAAD) is a life-threatening cardiovascular disorder.
Endoplasmic reticulum stress (ERS) and vascular smooth muscle cell (VSMC) apoptosis are …

[HTML][HTML] ANGPTL8 deletion attenuates abdominal aortic aneurysm formation in ApoE−/− mice

H Yu, X Jiao, Y Yang, Q Lv, Z Du, L Li, C Hu… - Clinical …, 2023 - portlandpress.com
Angiopoietin-like protein 8 (ANGPTL8) plays important roles in lipid metabolism, glucose
metabolism, inflammation, and cell proliferation and migration. Clinical studies have indicated …

[HTML][HTML] Metabolic systems approaches update molecular insights of clinical phenotypes and cardiovascular risk in patients with homozygous familial …

Z Du, F Li, L Jiang, L Li, Y Du, H Yu, Y Luo, Y Wang… - BMC medicine, 2023 - Springer
Background Homozygous familial hypercholesterolemia (HoFH) is an orphan metabolic
disease characterized by extremely elevated low-density lipoprotein cholesterol (LDL-C), …

SUMOylation inhibitors activate anti-tumor immunity by reshaping the immune microenvironment in a preclinical model of hepatocellular carcinoma

Z Wang, B Pan, L Su, H Yu, X Wu, Y Yao, X Zhang… - Cellular Oncology, 2023 - Springer
Purpose High levels of heterogeneity and immunosuppression characterize the HCC
immune microenvironment (TME). Unfortunately, the majority of hepatocellular carcinoma (HCC) …

Genetic diversity and relationship of endangered plant Magnolia officinalis (Magnoliaceae) assessed with ISSR polymorphisms

HH Yu, ZL Yang, B Sun, R Liu - Biochemical Systematics and Ecology, 2011 - Elsevier
Twenty-eight populations of the rare medicinal plant Magnolia officinalis (Magnoliaceae)
were sampled across its natural range, and inter-simple sequence repeats (ISSRs) markers …