Background Much uncertainty exists about the role of dietary glycemic index and glycemic
load in the development of type 2 diabetes mellitus, especially in populations that traditionally …

Importance Controlled studies have shown short-term efficacy of esketamine for treatment-resistant
depression (TRD), but long-term effects remain to be established. Objective To …

Soy food intake has been shown to have beneficial effects on cardiovascular disease risk
factors. Data directly linking soy food intake to clinical outcomes of cardiovascular disease, …

Background Soy consumption has been shown to modulate bone turnover and increase bone
mineral density in postmenopausal women. To our knowledge, no published studies have …

Background: Soy food is a rich source of isoflavones—a class of phytoestrogens that has
both antiestrogenic and anticarcinogenic properties. Objective: The objective was to evaluate …

Background: Asian populations habitually consume a large amount of cruciferous vegetables
and other plant-based foods. Few epidemiologic investigations have evaluated the …

We examined associations between fruit and vegetable intake and the incidence of type 2
diabetes (T2D) in a population-based prospective study of 64,191 women with no history of …

Background: Diet plays a key role in the development of type 2 diabetes (T2D), but little is
known about the contributions of specific nutrients in populations in which dietary patterns …

We report proteogenomic analysis of diffuse gastric cancers (GCs) in young populations.
Phosphoproteome data elucidated signaling pathways associated with somatic mutations …

Cyclooxygenase-2 (COX-2) is an important cellular target for both therapy and/or prevention
of inflammatory disorders and cancer. The advent of selective COX-2 inhibitors now allows …