We identified in-frame fusion transcripts of KIF5B (the kinesin family 5B gene) and the RET
oncogene, which are present in 1–2% of lung adenocarcinomas (LADCs) from people from …

Regulation of the actin cytoskeleton may play a crucial role in cell motility and cancer
invasion. We have produced a monoclonal antibody (NCC- Lu-632, IgM, k) reactive with an …

Breast cancer patients often develop metastatic disease years after resection of the primary
tumor. The patients are asymptomatic because the disseminated cells appear to become …

Purpose: Detection of sentinel lymph node (SLN) metastasis in breast cancer patients has
conventionally been determined by intraoperative histopathologic examination of frozen …

… Kimio Ushijima, Hideaki Yahata, Hiroyuki Yoshikawa, Ikuo Konishi, Toshiharu Yasugi,
Toshiaki Saito, Toru Nakanishi, Hiroshi Sasaki, Fumitaka Saji, Tsuyoshi Iwasaka, Masayuki …

β-Catenin forms complexes with Tcf and Lef-1 and functions as a transcriptional activator
downstream of the Wnt signaling pathway. Activation of the pathway by stabilization of β-…

The purpose of the present study was to identify histological surrogate predictive markers of
pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) in triple-…

A subset (1% to 5%) of non-small-cell lung carcinomas harbors the EML4-ALK fusion gene.
Data from previous studies on the histomorphology of ALK-rearranged lung cancer are …

Thirty-nine patients with endometrioid adenocarcinoma (EA) and atypical hyperplasia (AH)
of the endometrium who received conservative treatment to preserve fertility were collected …

Yes-associated protein (YAP), the nuclear effector of the Hippo pathway, is a key regulator
of organ size and a candidate human oncogene located at chromosome 11q22. Since we …