The purpose of the present study was to identify histological surrogate predictive markers of
pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) in triple-…

The purpose of this study was to determine the safety, distribution, internal dosimetry, and
initial human epidermal growth factor receptor 2 (HER2)–positive tumor images of 64 Cu-…

Background The purpose of this study was to determine whether brain metastases from
HER2-positive breast cancer could be detected noninvasively using positron emission …

Molecular imaging can visualize the biological processes at the molecular and cellular
levels in vivo using certain tracers for specific molecular targets. Molecular imaging of breast …

Purpose Whether age and inter-individual variability of pharmacogenetics are risk factors for
paclitaxel-induced peripheral neuropathy (PIPN) is inconclusive. This study was conducted …

Background. Bone-modifying agents (BMAs) reduce the incidence of skeletal-related events
(SREs) and are thus recommended for breast cancer patients with bone metastases. …

Purpose We conducted phase I and tolerability studies to determine the maximum tolerated
dose (MTD) and recommended dose of nab-paclitaxel when administered weekly with solid …

Objectives: It was the aim of this study to investigate gender differences in the outcomes of
carboplatin and paclitaxel chemotherapy in patients with unresectable stage IIIB-IV non-small …

Background We conducted a multicenter phase I/II trial of olaparib plus eribulin in Japanese
patients with advanced or metastatic triple-negative breast cancer (TNBC) to determine the …

Objective Trastuzumab emtansine (T-DM1), an antibody–drug conjugate composed of the
cytotoxic agent DM1 conjugated to trastuzumab via a stable thioether linker, has shown …