MicroRNA let-7c inhibits migration and invasion of human non-small cell lung cancer by targeting ITGB3 and MAP4K3

B Zhao, H Han, J Chen, Z Zhang, S Li, F Fang, Q Zheng… - Cancer letters, 2014 - Elsevier
MicroRNAs play an important regulatory role in carcinogenesis and cancer metastasis.
Different members of let-7 family have been reported to be decreased in human lung tumors. …

[PDF][PDF] 1B50-1, a mAb raised against recurrent tumor cells, targets liver tumor-initiating cells by binding to the calcium channel α2δ1 subunit

W Zhao, L Wang, H Han, K Jin, N Lin, T Guo, Y Chen… - Cancer cell, 2013 - cell.com
The identification and targeted therapy of cells involved in hepatocellular carcinoma (HCC)
recurrence remain challenging. Here, we generated a monoclonal antibody against recurrent …

Upregulation of myosin Va by Snail is involved in cancer cell migration and metastasis

L Lan, H Han, H Zuo, Z Chen, Y Du… - … Journal of Cancer, 2010 - Wiley Online Library
Cell migration, which involves acto‐myosin dynamics, cell adhesion, membrane trafficking
and signal transduction, is a prerequisite for cancer cell metastasis. Here, we report that an …

[HTML][HTML] PBX3 is targeted by multiple miRNAs and is essential for liver tumour-initiating cells

H Han, Y Du, W Zhao, S Li, D Chen, J Zhang… - Nature …, 2015 - nature.com
Tumour-initiating cells (TICs) are advocated to constitute the sustaining force to maintain and
renew fully established malignancy; however, the molecular mechanisms responsible for …

[HTML][HTML] CD44 promotes cell proliferation in non-small cell lung cancer

B Hu, Y Ma, Y Yang, L Zhang, H Han… - Oncology …, 2018 - spandidos-publications.com
Cluster of differentiation 44 (CD44), a marker for cancer stem cells, has been reported to be
associated with poor prognosis in non‑small cell lung cancer (NSCLC), but its involvement in …

[HTML][HTML] MicroRNA-200b is downregulated and suppresses metastasis by targeting LAMA4 in renal cell carcinoma

…, B Guan, J Liu, Z Zhang, S He, Y Zhan, B Su, H Han… - …, 2019 - thelancet.com
Background Metastasis is the primary cause of tumor death in renal cell carcinoma (RCC).
Improved diagnostic markers of metastasis are critically needed for RCC. MicoRNAs are …

MicroRNA‐130a‐3p suppresses cell migration and invasion by inhibition of TBL1XR1‐mediated EMT in human gastric carcinoma

S Wang, H Han, Y Hu, W Yang, Y Lv… - Molecular …, 2018 - Wiley Online Library
MiR‐130a‐3p was found to play tumor suppressor role in most human cancers, except for
gastric cancer. However, in this study, we demonstrated that miR‐130a‐3p was significantly …

Photoluminescence of Eu single doped and Eu/Dy codoped Sr2Al2SiO7 phosphors with long persistence

Y Ding, Y Zhang, Z Wang, W Li, D Mao, H Han… - Journal of …, 2009 - Elsevier
This paper reports the preparation of long persistent Sr 2 Al 2 SiO 7 :Eu 2+ and Sr 2 Al 2 SiO
7 :Eu 2+ , Dy 3+ phosphors and the comparison of their photoluminescent properties. The …

[HTML][HTML] Silencing Snail suppresses tumor cell proliferation and invasion by reversing epithelial-to-mesenchymal transition and arresting G2/M phase in non-small cell …

X Yang, M Han, H Han, B Wang… - International …, 2017 - spandidos-publications.com
Epithelial-to-mesenchymal transition (EMT) is essential for tumor invasion and metastasis.
Snail has been proven to be a key regulator of EMT. Several studies have shown compelling …

Let-7d inhibits intratumoral macrophage M2 polarization and subsequent tumor angiogenesis by targeting IL-13 and IL-10

B Su, H Han, Y Gong, X Li, C Ji, J Yao, J Yang… - Cancer Immunology …, 2021 - Springer
The microRNA let-7d has been reported to be a tumor suppressor in renal cell carcinoma (RCC).
Tumor-associated macrophages (TAM) are M2-polarized macrophages that can …